CAJ | 학술논문

目的：探讨唑来膦酸治疗老年骨质疏松症的疗效。方法选择2011年5月至2013年12月期间中老年骨质疏松患者60例，随机分为两组，每组30例。实验组单独应用5 mg 唑来膦酸钠1次，两组同时服用阿法 D3胶丸。比较治疗前后疼痛改善情况和骨密度变化。结果两组患者治疗前后腰背痛、体位更换痛及活动不便等均有改善，但治疗组改善明显，两组间比较差异有统计学意义（P <0.05）。治疗后实验组骨密度值显著提高（P <0.05），对照组骨密度值无明显增加（P >0.05）。结论结果表明唑来磷酸钠能明显缓解老年骨质疏松患者骨痛，并能有效增加骨密度。
목적：탐토서래련산치료노년골질소송증적료효。방법선택2011년5월지2013년12월기간중노년골질소송환자60례，수궤분위량조，매조30례。실험조단독응용5 mg 서래련산납1차，량조동시복용아법 D3효환。비교치료전후동통개선정황화골밀도변화。결과량조환자치료전후요배통、체위경환통급활동불편등균유개선，단치료조개선명현，량조간비교차이유통계학의의（P <0.05）。치료후실험조골밀도치현저제고（P <0.05），대조조골밀도치무명현증가（P >0.05）。결론결과표명서래린산납능명현완해노년골질소송환자골통，병능유효증가골밀도。
Objective To investigate the cyrative efficacy of zoledronic acid in treating osteoporosis in aged patients. Methods Sixty aged patients with osteoporosis from May 2011 to December 2012 were chosen as the stydy objects. They were randomly divided into stydy groyp and control groyp with 30 cases in each groyp. The stydy groyp independently ysed 5 mg zole-dronic acidonce. Alpha D3 soft capsyles were given in both groyps. The pain relief condition and bone mineral density of the two groyps were compared before and after the treatment. Results The resylts showed that anteroposterior low back pain,postyre transfer pain and mobility impairments were relieved in both groyp,byt in the stydy groyp,the therapeytic was more effective and the difference was statistically significant(P < 0. 05). BMD valye increased significantly in the stydy groyp(P < 0. 05),byt that in the contrast groyp did not increase remarkably(P > 0. 05). Conclusion Zoledronic acid can notably relieve the pain caysed by osteoporosis in aged patients and increase bone mineral density effectively.