中华眼底病杂志
中華眼底病雜誌
중화안저병잡지
CHINESE JOURNAL OF OCULAR FUNDUS DISEASES
2015年
4期
352-354
,共3页
薛康%钱江%岳晗%任慧%郭洁
薛康%錢江%嶽晗%任慧%郭潔
설강%전강%악함%임혜%곽길
视网膜母细胞瘤/诊断%检眼镜检查%超声检查
視網膜母細胞瘤/診斷%檢眼鏡檢查%超聲檢查
시망막모세포류/진단%검안경검사%초성검사
Retinoblastoma/diagnosis%Ophthalmoscopy%Ultrasonography
目的：观察第三代广角数码视网膜成像系统(RetCam Ⅲ)在视网膜母细胞瘤(RB)检查诊断中的应用价值。方法回顾性研究。2012年1月至2014年5月临床确诊为 RB 的94例患者125只眼纳入研究。所有患者均行 RetCam Ⅲ、双目间接检眼镜及 B 型超声检查。以双目间接检眼镜检查结果作为“金标准”,对比分析 RetCam Ⅲ和双目间接检眼镜检查结对 RB 分期的一致性以及 RetCam Ⅲ、双目间接检眼镜及 B 型超声检查对 A~D 期不同分期瘤体的检出率。结果双目间接检眼镜检查发现,125只眼中,A 期18只眼,占14.4%；B 期15只眼,占12.0%；C 期10只眼,占8.0%；D 期28只眼,占22.4%；E 期54只眼,占43.2%。RetCam Ⅲ检查发现,125只眼中,A 期18只眼,占14.4%；B 期16只眼,占12.8%；C 期11只眼,占8.8%；D 期27只眼,占21.6%；E 期53只眼,占42.4%。Kappa 系数检验分析结果显示, RetCam Ⅲ与双目间接检眼镜检查结果在 RB 分期中一致性良好(加权 Kappa 系数=0.9798,95%可信区间为0.9601~0.9995)。双目间接检眼镜检查发现,125只患眼中,A ~ D 期共71只眼150个瘤体。RetCam Ⅲ检查检出瘤体数为147个,检出率为98.0%。未检出的3个瘤体均位于周边接近锯齿缘视网膜处。B 型超声检查检出瘤体数为122个,检出率为81.3%。RetCam Ⅲ检查过程中,未见角膜挫伤、玻璃体积血、视网膜出血、呼吸暂停、心跳骤停等局部或全身并发症发生。结论RetCam Ⅲ可有效检出各种分期的 RB,与双目间接检眼镜检查结果的一致性良好。
目的：觀察第三代廣角數碼視網膜成像繫統(RetCam Ⅲ)在視網膜母細胞瘤(RB)檢查診斷中的應用價值。方法迴顧性研究。2012年1月至2014年5月臨床確診為 RB 的94例患者125隻眼納入研究。所有患者均行 RetCam Ⅲ、雙目間接檢眼鏡及 B 型超聲檢查。以雙目間接檢眼鏡檢查結果作為“金標準”,對比分析 RetCam Ⅲ和雙目間接檢眼鏡檢查結對 RB 分期的一緻性以及 RetCam Ⅲ、雙目間接檢眼鏡及 B 型超聲檢查對 A~D 期不同分期瘤體的檢齣率。結果雙目間接檢眼鏡檢查髮現,125隻眼中,A 期18隻眼,佔14.4%；B 期15隻眼,佔12.0%；C 期10隻眼,佔8.0%；D 期28隻眼,佔22.4%；E 期54隻眼,佔43.2%。RetCam Ⅲ檢查髮現,125隻眼中,A 期18隻眼,佔14.4%；B 期16隻眼,佔12.8%；C 期11隻眼,佔8.8%；D 期27隻眼,佔21.6%；E 期53隻眼,佔42.4%。Kappa 繫數檢驗分析結果顯示, RetCam Ⅲ與雙目間接檢眼鏡檢查結果在 RB 分期中一緻性良好(加權 Kappa 繫數=0.9798,95%可信區間為0.9601~0.9995)。雙目間接檢眼鏡檢查髮現,125隻患眼中,A ~ D 期共71隻眼150箇瘤體。RetCam Ⅲ檢查檢齣瘤體數為147箇,檢齣率為98.0%。未檢齣的3箇瘤體均位于週邊接近鋸齒緣視網膜處。B 型超聲檢查檢齣瘤體數為122箇,檢齣率為81.3%。RetCam Ⅲ檢查過程中,未見角膜挫傷、玻璃體積血、視網膜齣血、呼吸暫停、心跳驟停等跼部或全身併髮癥髮生。結論RetCam Ⅲ可有效檢齣各種分期的 RB,與雙目間接檢眼鏡檢查結果的一緻性良好。
목적：관찰제삼대엄각수마시망막성상계통(RetCam Ⅲ)재시망막모세포류(RB)검사진단중적응용개치。방법회고성연구。2012년1월지2014년5월림상학진위 RB 적94례환자125지안납입연구。소유환자균행 RetCam Ⅲ、쌍목간접검안경급 B 형초성검사。이쌍목간접검안경검사결과작위“금표준”,대비분석 RetCam Ⅲ화쌍목간접검안경검사결대 RB 분기적일치성이급 RetCam Ⅲ、쌍목간접검안경급 B 형초성검사대 A~D 기불동분기류체적검출솔。결과쌍목간접검안경검사발현,125지안중,A 기18지안,점14.4%；B 기15지안,점12.0%；C 기10지안,점8.0%；D 기28지안,점22.4%；E 기54지안,점43.2%。RetCam Ⅲ검사발현,125지안중,A 기18지안,점14.4%；B 기16지안,점12.8%；C 기11지안,점8.8%；D 기27지안,점21.6%；E 기53지안,점42.4%。Kappa 계수검험분석결과현시, RetCam Ⅲ여쌍목간접검안경검사결과재 RB 분기중일치성량호(가권 Kappa 계수=0.9798,95%가신구간위0.9601~0.9995)。쌍목간접검안경검사발현,125지환안중,A ~ D 기공71지안150개류체。RetCam Ⅲ검사검출류체수위147개,검출솔위98.0%。미검출적3개류체균위우주변접근거치연시망막처。B 형초성검사검출류체수위122개,검출솔위81.3%。RetCam Ⅲ검사과정중,미견각막좌상、파리체적혈、시망막출혈、호흡잠정、심도취정등국부혹전신병발증발생。결론RetCam Ⅲ가유효검출각충분기적 RB,여쌍목간접검안경검사결과적일치성량호。
Objective To observe the application value of RetCam Ⅲ in the diagnosis of retinoblastoma (RB).Methods The clinical data of 125 eyes from 94 patients with RB were retrospectively analyzed.According to the International Intraocular Retinoblastoma Classification,the results of binocular indirect ophthalmoscope and RetCam Ⅲ was compared.The consistency between RetCam Ⅲ and binocular indirect ophthalmoscope was analyzed by Kappa test.The detectable rates of tumor between binocular indirect ophthalmoscope,RetCam Ⅲ and B scan ultrasound were comparatively analyzed.Results By binocular indirect ophthalmoscope,there were 18 eyes (14.4%)in stage A,1 5 eyes (12.0%)in stage B, 10 eyes (8.0%)in stage C,28 eyes (22.4%)in stage D,and 54 eyes (43.2%)in stage E.Using RetCam Ⅲ,the classification was 18 eyes (14.4%)in stage A,1 6 eyes (12.8%)in stage B,1 1 eyes (8.8%)in stage C,27 eyes (21.6%)in stage D,and 53 eyes (42.4%)in stage E.The RB classification of RetCam Ⅲ was quite consistent with binocular indirect ophthalmoscope (Weighted Kappa Coefficient =0.979 8,95% confidence interval = 0.960 1 - 0.999 5).A total of 1 50 tumors from stage A - D were observed by binocular indirect ophthalmoscope.In which,147 tumors (98.0%)were found by RetCam Ⅲ, 122 tumors (81.3%) were found by B scan ultrasound.No serious complication was found in these patients.Conclusions RetCam Ⅲ can detect RB of different stage in clinic.It is quite consistent with binocular indirect ophthalmoscope.
