中华眼底病杂志
中華眼底病雜誌
중화안저병잡지
CHINESE JOURNAL OF OCULAR FUNDUS DISEASES
2015年
4期
355-358
,共4页
彭婕%张琦%费萍%黄秋婧%李忆安%赵培泉
彭婕%張琦%費萍%黃鞦婧%李憶安%趙培泉
팽첩%장기%비평%황추청%리억안%조배천
视神经疾病/诊断%视盘/畸形%荧光素血管造影术
視神經疾病/診斷%視盤/畸形%熒光素血管造影術
시신경질병/진단%시반/기형%형광소혈관조영술
Optic nerve diseases/ diagnosis%Optic disk/abnormalities%Fluorescein angiography
目的：观察儿童牵牛花综合征(MGS)患眼荧光素眼底血管造影(FFA)特征。方法临床确诊为 MGS 的14例患儿14只眼纳入研究。其中,男性、女性各7例7只眼。合并永存原始玻璃体增生症4只眼,占28.57%；合并视网膜脱离4只眼,占28.57%,均未见视网膜裂孔；合并视盘旁视网膜下黄白色渗出1只眼,占7.14%。所有患儿应用第三代广角数码视网膜成像仪行眼底及 FFA 检查。测量患眼及对侧健康眼视盘纵轴、横轴长度。记录臂-视网膜循环时间(A-RCT),观察患眼及对侧健康眼视盘边缘显影血管数量、视网膜血管形态及走形、周边部视网膜无灌注区等异常情况。选择同期行 FFA 检查诊断为眼底正常的16名儿童作为对照组。对比分析患眼与对照组受检眼 A-RCT 的情况。结果患眼视盘纵轴长度是对侧健康眼的1.58~3.31倍,平均(2.56±0.58)倍；视盘横轴长度是对侧健康眼的1.18~3.70倍,平均(2.73±0.60)倍。FFA 检查发现,患眼 A-RCT 为9.83~16.56 s,平均 A-RCT 为(13.25±4.10)s。对照组受检眼 A-RCT 为5.83~13.44 s,平均 A-RCT 为(9.34±2.20)s。患眼 A-RCT 较对照组受检眼明显延迟。早期患眼视盘呈弱荧光,视盘周围色素遮蔽呈弱荧光,其外侧不规则视网膜脉络膜萎缩区呈强荧光环；晚期视盘组织着染呈强荧光。患眼、对侧健康眼视盘边缘处显影血管平均数分别为(30.27±4.86)、(15.83±1.95)支。患眼视盘边缘处显影血管数明显多于对侧健康眼。所有患眼均存在周边部视网膜无灌注区。结论MGS 患眼 FFA 特征为视盘扩大,视盘边缘显影血管数量增多,A-RCT 延迟及周边部视网膜无灌注区。
目的：觀察兒童牽牛花綜閤徵(MGS)患眼熒光素眼底血管造影(FFA)特徵。方法臨床確診為 MGS 的14例患兒14隻眼納入研究。其中,男性、女性各7例7隻眼。閤併永存原始玻璃體增生癥4隻眼,佔28.57%；閤併視網膜脫離4隻眼,佔28.57%,均未見視網膜裂孔；閤併視盤徬視網膜下黃白色滲齣1隻眼,佔7.14%。所有患兒應用第三代廣角數碼視網膜成像儀行眼底及 FFA 檢查。測量患眼及對側健康眼視盤縱軸、橫軸長度。記錄臂-視網膜循環時間(A-RCT),觀察患眼及對側健康眼視盤邊緣顯影血管數量、視網膜血管形態及走形、週邊部視網膜無灌註區等異常情況。選擇同期行 FFA 檢查診斷為眼底正常的16名兒童作為對照組。對比分析患眼與對照組受檢眼 A-RCT 的情況。結果患眼視盤縱軸長度是對側健康眼的1.58~3.31倍,平均(2.56±0.58)倍；視盤橫軸長度是對側健康眼的1.18~3.70倍,平均(2.73±0.60)倍。FFA 檢查髮現,患眼 A-RCT 為9.83~16.56 s,平均 A-RCT 為(13.25±4.10)s。對照組受檢眼 A-RCT 為5.83~13.44 s,平均 A-RCT 為(9.34±2.20)s。患眼 A-RCT 較對照組受檢眼明顯延遲。早期患眼視盤呈弱熒光,視盤週圍色素遮蔽呈弱熒光,其外側不規則視網膜脈絡膜萎縮區呈彊熒光環；晚期視盤組織著染呈彊熒光。患眼、對側健康眼視盤邊緣處顯影血管平均數分彆為(30.27±4.86)、(15.83±1.95)支。患眼視盤邊緣處顯影血管數明顯多于對側健康眼。所有患眼均存在週邊部視網膜無灌註區。結論MGS 患眼 FFA 特徵為視盤擴大,視盤邊緣顯影血管數量增多,A-RCT 延遲及週邊部視網膜無灌註區。
목적：관찰인동견우화종합정(MGS)환안형광소안저혈관조영(FFA)특정。방법림상학진위 MGS 적14례환인14지안납입연구。기중,남성、녀성각7례7지안。합병영존원시파리체증생증4지안,점28.57%；합병시망막탈리4지안,점28.57%,균미견시망막렬공；합병시반방시망막하황백색삼출1지안,점7.14%。소유환인응용제삼대엄각수마시망막성상의행안저급 FFA 검사。측량환안급대측건강안시반종축、횡축장도。기록비-시망막순배시간(A-RCT),관찰환안급대측건강안시반변연현영혈관수량、시망막혈관형태급주형、주변부시망막무관주구등이상정황。선택동기행 FFA 검사진단위안저정상적16명인동작위대조조。대비분석환안여대조조수검안 A-RCT 적정황。결과환안시반종축장도시대측건강안적1.58~3.31배,평균(2.56±0.58)배；시반횡축장도시대측건강안적1.18~3.70배,평균(2.73±0.60)배。FFA 검사발현,환안 A-RCT 위9.83~16.56 s,평균 A-RCT 위(13.25±4.10)s。대조조수검안 A-RCT 위5.83~13.44 s,평균 A-RCT 위(9.34±2.20)s。환안 A-RCT 교대조조수검안명현연지。조기환안시반정약형광,시반주위색소차폐정약형광,기외측불규칙시망막맥락막위축구정강형광배；만기시반조직착염정강형광。환안、대측건강안시반변연처현영혈관평균수분별위(30.27±4.86)、(15.83±1.95)지。환안시반변연처현영혈관수명현다우대측건강안。소유환안균존재주변부시망막무관주구。결론MGS 환안 FFA 특정위시반확대,시반변연현영혈관수량증다,A-RCT 연지급주변부시망막무관주구。
Objective To observe the fundus fluorescein angiography (FFA) manifestations of pediatric morning glory syndrome (MGS)patients.Methods Fourteen eyes diagnosed as MGS of 14 patients were studied.Among the 14 cases,there were 7 male and 7 female patients.At the time of FFA, the mean age of the patients was (38.75±33.91)months old,ranging from 5.5 to 128.0 months.Among the 14 eyes,four (28.57%)were associated with persistent hyperplastic primary vitreous;four (28.57%) were associated with retinal detachment with no retinal breaks,and one (7.14%)was associated with peripapillary subretinal exudation.All patients underwent peripapillary laser photocoagulation under general anesthesia first and then FFA with the third generation of wide-angle digital retinal imaging system.The arm-retinal circulation time (A-RCT),numbers of blood vessels on the edges of optic disc of the MGS eyes and the contralateral healthy eyes, retinal vascular morphology, the peripheral avascular area, neovascularization,retinal detachment and other abnormalities were documented.The horizontal and vertical diameters of the optic disc of the affected eyes and the contralateral healthy eyes were measured.To compare the A-RCT,1 6 children with normal FFA were selected as control group.Results The diameters of the vertical and horizontal axis of the affected eyes were as (2.56 ± 0.58 )and (2.73 ± 0.60 )times of the contralateral healthy eyes respectively.The average A-RCT of the affected eyes and eyes of the control group were (13.25±4.10)and (9.34±2.20)s respectively.The affected eyes had significantly prolonged A-RCT.At early stage,the optic disc and peripapillary areas showed hypo-fluorescence,while the irregular retinochoroidal atrophy area outside of the optic disk manifested as hyper-fluorescence ring.At late stage, optic disc showed hyper-fluorescence.Numbers of blood vessels on the edge of the optic disc of the affected eyes and contralateral healthy eyes were 30.27 ±4.86 and 1 5.83 ±1.95 respectively,the affected eyes had much more vessels than the contralateral healthy eyes.All affected eyes had peripheral retinal non-perfusion areas.Conclusion FFA examination showed prolonged A-RCT and peripheral retinal non-perfusion areas in the affected MGS eyes.
