国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2015年
16期
2405-2407
,共3页
2型糖尿病%25-羟维生素D%二甲双胍
2型糖尿病%25-羥維生素D%二甲雙胍
2형당뇨병%25-간유생소D%이갑쌍고
Type 2 diabetes mellitus%25-hydroxy-vitamin D%Metformin
目的 观察初诊2型糖尿病患者的25-羟维生素D水平以及二甲双胍对其的影响.方法 选取我院2013年1月至12月住院的50例初诊2型糖病患者为研究对象(糖尿病组).同时选取50名性别、年龄相匹配的对照者作为对照组,然后记录受试者的一般情况、空腹血糖、餐后2小时血糖、糖化血红蛋白、血脂情况并检测25-羟维生素D情况,糖尿病组给予口服二甲双胍0.5 g bid治疗,并在服药后的第3个月和第6个月进行血糖和25-羟维生素D的检测.结果 50例初诊2型糖患者的25-羟维生素D水平为(39.41±6.78) nmol/L,较对照组的(112.00± 16.10) nmol/L明显下降.2型糖患者经过二甲双胍治疗3个月和6个月后,25-羟维生素D水平分别为(60.79±12.83) nmol/L和(95.01±13.76) nmol/L,均高于治疗前.结论 初诊2型糖尿病患者的25-羟维生素D明显下降,给予二甲双胍治疗后,有不同程度的回升.
目的 觀察初診2型糖尿病患者的25-羥維生素D水平以及二甲雙胍對其的影響.方法 選取我院2013年1月至12月住院的50例初診2型糖病患者為研究對象(糖尿病組).同時選取50名性彆、年齡相匹配的對照者作為對照組,然後記錄受試者的一般情況、空腹血糖、餐後2小時血糖、糖化血紅蛋白、血脂情況併檢測25-羥維生素D情況,糖尿病組給予口服二甲雙胍0.5 g bid治療,併在服藥後的第3箇月和第6箇月進行血糖和25-羥維生素D的檢測.結果 50例初診2型糖患者的25-羥維生素D水平為(39.41±6.78) nmol/L,較對照組的(112.00± 16.10) nmol/L明顯下降.2型糖患者經過二甲雙胍治療3箇月和6箇月後,25-羥維生素D水平分彆為(60.79±12.83) nmol/L和(95.01±13.76) nmol/L,均高于治療前.結論 初診2型糖尿病患者的25-羥維生素D明顯下降,給予二甲雙胍治療後,有不同程度的迴升.
목적 관찰초진2형당뇨병환자적25-간유생소D수평이급이갑쌍고대기적영향.방법 선취아원2013년1월지12월주원적50례초진2형당병환자위연구대상(당뇨병조).동시선취50명성별、년령상필배적대조자작위대조조,연후기록수시자적일반정황、공복혈당、찬후2소시혈당、당화혈홍단백、혈지정황병검측25-간유생소D정황,당뇨병조급여구복이갑쌍고0.5 g bid치료,병재복약후적제3개월화제6개월진행혈당화25-간유생소D적검측.결과 50례초진2형당환자적25-간유생소D수평위(39.41±6.78) nmol/L,교대조조적(112.00± 16.10) nmol/L명현하강.2형당환자경과이갑쌍고치료3개월화6개월후,25-간유생소D수평분별위(60.79±12.83) nmol/L화(95.01±13.76) nmol/L,균고우치료전.결론 초진2형당뇨병환자적25-간유생소D명현하강,급여이갑쌍고치료후,유불동정도적회승.
Objective To observe the level of25-hydroxy-vitamin D of newly diagnosed type 2 diabetics mellitus (T2DM) patients and the influence of metformin on it.Methods 50 newly diagnosed T2DM patients in our hospital from January to December 2013 were selected,50 sex-and age-matched healthy people were selected as control.The general condition,fasting plasma glucose (FPG),2-hour postprandial blood glucose (2hPBG),glycosylated hemoglobin (HbA1c),lipid profile were recorded and the level of 25-hydroxy-vitamin D was detected.T2DM patients were given orally metformin 0.5 g bid,and detected the levels of blood glucose and 25-hydroxy-vitamin D after 3,6 months.Results The level of serum 25-hydroxy-vitamin D in T2DM patients was (39.41±6.78) nmol/L,significantly lower than (112.00±16.10) nmol/L in control group.The level of serum 25-hydroxy-vitamin D was (60.79±12.83) nmol/L and (95.01±13.76) nmol/L respectively after 3,6 months' treatment.Conclusions The level of 25-hydroxy-vitamin D significantly decreased in patients with newly diagnosed type 2 diabetes mellitus,and metformin treatment can partially reverse this trend.
