CAJ | 학술논문

目的了解我院发生的不良反应(ADR)的特点和一般规律,保障临床用药安全和促进临床合理用药.方法整理我院2014年度上报国家不良反应中心的ADR报告389份,从患者年龄、药品种类、给药途径、累及器官或系统、临床表现等方面统计,分析.结果 389例药品不良反应中,中老年患者(＞ 50岁)发生ADR比例较多,占58.35％;给药方式以静脉滴注方式给药为主,占66.58％;抗感染类药品不良反应发生率最高,占30.08％;发生药品不良反应的患者常有多系统损害表现,受累组织以皮肤及其附件损害和全身性损害为多,分别占36.25％和19.02％.结论临床用药应重视不良反应的监测,规范用药,以减少不良反应的发生,保证患者用药安全.
목적 료해아원발생적불량반응(ADR)적특점화일반규률,보장림상용약안전화촉진림상합리용약.방법 정리아원2014년도상보국가불량반응중심적ADR보고389빈,종환자년령、약품충류、급약도경、루급기관혹계통、림상표현등방면통계,분석.결과 389례약품불량반응중,중노년환자(＞ 50세)발생ADR비례교다,점58.35％;급약방식이정맥적주방식급약위주,점66.58％;항감염류약품불량반응발생솔최고,점30.08％;발생약품불량반응적환자상유다계통손해표현,수루조직이피부급기부건손해화전신성손해위다,분별점36.25％화19.02％.결론 림상용약응중시불량반응적감측,규범용약,이감소불량반응적발생,보증환자용약안전.
Objective To analyze the characteristics of ADRs in our hospital,so as to promote rational use of drugs.Method 389 ADR reports of our hospital in 2014 were collected and analyzed statistically.Results Patients aged over 50 years old were more susceptible to ADR (58.35％ of ADR reports).Intravenous administration took a great amount of 66.58％ among ADR reports.30.08％ of ADR cases were caused by antibiotics.The main manifestations were lesion of skin and its accessories and systemic damage which took 36.25％ and 19.02％.Conclusion ADR monitoring and rational use of drugs should be emphasized in clinic activities so as to reduce ADRs.