CAJ | 학술논문

目的探讨幽门螺杆菌感染与反流性食管炎发生的相关性。方法选取2013年4月至2014年12月，在新疆维吾尔自治区人民医院就诊的150例反流性食管炎患者与同期在我院就诊的慢性萎缩性胃炎患者150例，比较二组患者的幽门螺杆菌感染阳性率，并且对幽门螺杆菌与反流性食管炎进行相关性分析。结果反流性食管炎组患者和慢性萎缩性胃炎组患者的幽门螺杆菌阳性率分别为44．7％和65．3％，差异有统计学意义（χ2＝13．42，P＜0．05）。幽门螺杆菌阴性的中、重度反流性食管炎发生率相比幽门螺杆菌阳性的中、重度反流性食管炎的发生率略高。结论幽门螺杆菌可能对反流性食管炎的发病有一定的保护作用。
목적탐토유문라간균감염여반류성식관염발생적상관성。방법선취2013년4월지2014년12월，재신강유오이자치구인민의원취진적150례반류성식관염환자여동기재아원취진적만성위축성위염환자150례，비교이조환자적유문라간균감염양성솔，병차대유문라간균여반류성식관염진행상관성분석。결과반류성식관염조환자화만성위축성위염조환자적유문라간균양성솔분별위44．7％화65．3％，차이유통계학의의（χ2＝13．42，P＜0．05）。유문라간균음성적중、중도반류성식관염발생솔상비유문라간균양성적중、중도반류성식관염적발생솔략고。결론유문라간균가능대반류성식관염적발병유일정적보호작용。
[Abstrac t] Objective To study the correlation analysis of Helicobacter pylori(Hp) infection and reflux esophagitis .Methods A total of 150 patients with reflux esophagitis were enrolled into this study in our hospital between April 2013 and December 2014,at the same time in our hospital 150 cases of patients with chronic atrophic gastritis were collected .The positive rates of Hp in the two groups were compared and analyzed.And we also conducted correlative analysis of Hp and reflux esophagitis in this study .Results The positive rate of Hp was 44.7%and 65.3%,respectively,the difference was statistically significant (χ2 =13.42, P<0.05).Severe reflux esophagitis incidence was higher in negative Hp than the positive.Conclusion Hp may has certain protective effect on the incidence of reflux esophagitis .