CAJ | 학술논문

RhD母儿血型不合是指来自RhD阴性母体的抗体破坏了RhD阳性胎儿的红细胞，造成胎儿或新生儿溶血，严重者可导致死胎。在广泛应用抗D免疫球蛋白以前，胎儿或新生儿严重溶血发生率很高。规范使用抗D免疫球蛋白预防母儿血型不合和孕期严密监测胎儿状态是降低围产儿发病率和死亡率的关键。
RhD모인혈형불합시지래자RhD음성모체적항체파배료RhD양성태인적홍세포，조성태인혹신생인용혈，엄중자가도치사태。재엄범응용항D면역구단백이전，태인혹신생인엄중용혈발생솔흔고。규범사용항D면역구단백예방모인혈형불합화잉기엄밀감측태인상태시강저위산인발병솔화사망솔적관건。
Fetal-maternal hemorrhage of RhD isoimmunization is maternal antibodies of Rh-negative pregnant woman affecting the RhD red cell antigen of Rh-positive fetus, which may result in hemolytic disease of the fetus/newborn, even stillbirth.Prior to the use of anti-D immune globulin, the incidence rate of the fetus/newborn hemolytic disease is high.Implement RhD immune globulin prophylaxis normatively and monitor fetal during pregnancy carefully can led to a significant reduction in the frequency of perinatal mortality and morbidity.