CAJ | 학술논문

目的：研究参菊洗剂的体外抑菌作用。方法采用琼脂扩散纸片法测定抑菌圈直径,采用液体培养液连续稀释法测定最低抑菌浓度( MIC),采用琼脂培养液平板法测定最低杀菌浓度( MBC),并与市售某妇科洗液比较抑菌作用。结果参菊洗剂对5种病原菌株的抑菌作用明显优于相同浓度的市售某妇科洗液,差异有统计学意义(P<0.05)；参菊洗剂对金黄色葡萄球菌、铜绿假单胞菌、大肠埃希菌、枯草芽孢杆菌、白念珠菌的MIC分别为33.75,67.5,67.5,67.5,33.75 mg·mL-1；参菊洗剂对金黄色葡萄球菌、铜绿假单胞菌、大肠埃希菌、枯草芽孢杆菌、白念珠菌的MBC分别为33.75,67.5,67.5,135,33.75 mg·mL-1。结论参菊洗剂具有较明显的抑菌和杀菌作用。
목적：연구삼국세제적체외억균작용。방법채용경지확산지편법측정억균권직경,채용액체배양액련속희석법측정최저억균농도( MIC),채용경지배양액평판법측정최저살균농도( MBC),병여시수모부과세액비교억균작용。결과삼국세제대5충병원균주적억균작용명현우우상동농도적시수모부과세액,차이유통계학의의(P<0.05)；삼국세제대금황색포도구균、동록가단포균、대장애희균、고초아포간균、백념주균적MIC분별위33.75,67.5,67.5,67.5,33.75 mg·mL-1；삼국세제대금황색포도구균、동록가단포균、대장애희균、고초아포간균、백념주균적MBC분별위33.75,67.5,67.5,135,33.75 mg·mL-1。결론삼국세제구유교명현적억균화살균작용。
Objective To study the antibacterial effect of Shenju lotion in vitro. Methods The diameter of inhibition zone was determined by paper-disc agar-diffusion method. Minimum inhibitory concentration ( MIC) and Minimum bactericidal concentration ( MBC ) was determined by culture medium dilution methodand agar medium plate method, respectively. Antibacterial effect was compared between Shenju lotion and city sale of the gynecological lotion. Results Inhibitory effects of Shenju lotion on 5 pathogenic strains were significantly better than that of city sale of the gynecological lotion at the same concentrations (P<0. 05). MIC of Shenju lotion on Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Bacillus subtilis and Candida albicans was 33. 75, 67. 5, 67. 5, 67. 5 and 33. 75 mg ·mL-1 , respectively. MBC of Shenju lotion on Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Bacillus subtilis and Candida albicans was 33. 75, 67. 5, 67. 5, 135 and 33. 75 mg ·mL-1 , respectively. Conclusion Shenju lotion has obvious bacteriostasis and sterilization effect.