检验医学与临床
檢驗醫學與臨床
검험의학여림상
JOURNAL OF LABORATORY MEDICINE AND CLINICAL SCIENCES
2015年
15期
2208-2209,2211
,共3页
解脲支原体%精子形态%精子活力%男性不育
解脲支原體%精子形態%精子活力%男性不育
해뇨지원체%정자형태%정자활력%남성불육
ureaplasma urealyticum%sperm morphology and activity%male infertility
目的：通过对郑州地区解脲支原体感染患者精子形态的研究，探讨解脲支原体感染与不育男性精子形态之间的相关性，为临床诊断和治疗男性不育症提供参考。方法收集285例郑州市地区男性不育症患者的精液，并以是否感染解脲支原体分为阳性组和阴性组，比较2组精子的形态及活力，分析解脲支原体对男性不育的影响作用。结果解脲支原体阳性组精子头部和尾部畸形率高于阴性组，差异有统计学意义[头部畸形：（53．40±5．21）％，（50．10±4．35）％；尾部畸形：（8．70±2．31）％，（3．60±4．36）％；P＜0．05]；解脲支原体阳性组头部、体部和尾部畸形率都明显高于正常组，差异有统计学意义[头部畸形：（53．40±5．21）％，（34．20±3．78）％；体部畸形：（9．30±5．98）％，（4．50±5．31）％；尾部畸形：（8．70±2．31）％，（4．10±3．57）％；P＜0．05]；解脲支原体阳性组精子活力 A 级＋ B 级和 A 级百分率[（32．30±3．82）％，（12．50±4．45）％]均低于阴性组[（38．50±5．29）％，（14．60±3．67）％]，且明显低于正常组，差异有统计学意义[（55．00±4．95）％，（29．60±5．31）％；P＜0．05]。结论解脲支原体感染能够影响精子形态和活力，从而导致男性不育。
目的：通過對鄭州地區解脲支原體感染患者精子形態的研究，探討解脲支原體感染與不育男性精子形態之間的相關性，為臨床診斷和治療男性不育癥提供參攷。方法收集285例鄭州市地區男性不育癥患者的精液，併以是否感染解脲支原體分為暘性組和陰性組，比較2組精子的形態及活力，分析解脲支原體對男性不育的影響作用。結果解脲支原體暘性組精子頭部和尾部畸形率高于陰性組，差異有統計學意義[頭部畸形：（53．40±5．21）％，（50．10±4．35）％；尾部畸形：（8．70±2．31）％，（3．60±4．36）％；P＜0．05]；解脲支原體暘性組頭部、體部和尾部畸形率都明顯高于正常組，差異有統計學意義[頭部畸形：（53．40±5．21）％，（34．20±3．78）％；體部畸形：（9．30±5．98）％，（4．50±5．31）％；尾部畸形：（8．70±2．31）％，（4．10±3．57）％；P＜0．05]；解脲支原體暘性組精子活力 A 級＋ B 級和 A 級百分率[（32．30±3．82）％，（12．50±4．45）％]均低于陰性組[（38．50±5．29）％，（14．60±3．67）％]，且明顯低于正常組，差異有統計學意義[（55．00±4．95）％，（29．60±5．31）％；P＜0．05]。結論解脲支原體感染能夠影響精子形態和活力，從而導緻男性不育。
목적：통과대정주지구해뇨지원체감염환자정자형태적연구，탐토해뇨지원체감염여불육남성정자형태지간적상관성，위림상진단화치료남성불육증제공삼고。방법수집285례정주시지구남성불육증환자적정액，병이시부감염해뇨지원체분위양성조화음성조，비교2조정자적형태급활력，분석해뇨지원체대남성불육적영향작용。결과해뇨지원체양성조정자두부화미부기형솔고우음성조，차이유통계학의의[두부기형：（53．40±5．21）％，（50．10±4．35）％；미부기형：（8．70±2．31）％，（3．60±4．36）％；P＜0．05]；해뇨지원체양성조두부、체부화미부기형솔도명현고우정상조，차이유통계학의의[두부기형：（53．40±5．21）％，（34．20±3．78）％；체부기형：（9．30±5．98）％，（4．50±5．31）％；미부기형：（8．70±2．31）％，（4．10±3．57）％；P＜0．05]；해뇨지원체양성조정자활력 A 급＋ B 급화 A 급백분솔[（32．30±3．82）％，（12．50±4．45）％]균저우음성조[（38．50±5．29）％，（14．60±3．67）％]，차명현저우정상조，차이유통계학의의[（55．00±4．95）％，（29．60±5．31）％；P＜0．05]。결론해뇨지원체감염능구영향정자형태화활력，종이도치남성불육。
Objective To investigate the relationship between ureaplasma urealyticum (UU ) infection and sperm morphology of male infertility by researching the sperm morphology in the patients with UU infection to pro‐vide a experimental reference for the clinical diagnosis and treatment of male infertility .Methods The semen from 285 cases of male infertility in Zhengzhou area and divided into the positive and negative groups according to whether UU infection .Then the morphology and vitality of sperms were compared between the two groups for analyzing the influence effect of UU on male infertility .Results The abnormalities rate of sperm head and tail in the UU positive group was higher than that in the UU negative group (sperm head abnormalities :[(53 .40 ± 5 .21)% ,(50 .10 ± 4 .35)% ;sperm tail abnormalities :(8 .70 ± 2 .31)% ,(3 .60 ± 4 .36)% ,P < 0 .05] .The abnormalities rates of sperm head ,body and tail in the UU positive group were significantly higher than those in the normal group ,the differences were statistically significant[sperm head abnormalities :(53 .40 ± 5 .21)% vs .(34 .20 ± 3 .78)% ;sperm body abnor‐malities :(9 .30 ± 5 .98)% vs .(4 .50 ± 5 .31)% ;sperm tail abnormalities :(8 .70 ± 2 .31)% vs .(4 .10 ± 3 .57)% ;P<0 .05] ;The percentages of sperm vitality grade A and A + B in the UU positive group were (32 .30 ± 3 .82)% and (12 .50 ± 4 .45)% ,which were lower than (38 .50 ± 5 .29)% and (14 .60 ± 3 .67)% in the UU negative group and all were lower than (55 .00 ± 4 .95)% ,(29 .60 ± 5 .31)% in the control group(P< 0 .05) .Conclusion UU infection can affect the morphology and activity of sperm ,thus results in male infertility .
