中华临床医师杂志（电子版）
中華臨床醫師雜誌（電子版）
중화림상의사잡지（전자판）
CHINESE JOURNAL OF CLINICIANS(ELECTRONIC VERSION)
2015年
14期
2649-2652
,共4页
柯群刚%黄继超%郝占伟%余仔军%朱双九%樊祥山
柯群剛%黃繼超%郝佔偉%餘仔軍%硃雙九%樊祥山
가군강%황계초%학점위%여자군%주쌍구%번상산
直肠肿瘤%淋巴转移%相关因素
直腸腫瘤%淋巴轉移%相關因素
직장종류%림파전이%상관인소
Rectal neoplasms%Lymphatic metastasis%Related factors
目的：探讨 T1～2期原发性直肠癌患者淋巴结转移的相关因素，为更好地确定直肠癌局部切除的适应人群奠定科学基础。方法选取在本院肿瘤外科住院行根治性手术的 T1～2期的原发性直肠癌且治疗的临床资料完整的患者82例，将患者的性别、年龄、肿瘤的直径、肿瘤的组织类型、肿瘤的大体类型、分化程度、浸润深度、T 分期以及术前癌胚抗原（CEA）水平等指标进行回顾性分析。结果肿瘤的组织类型、肿瘤的大体类型、分化程度、浸润深度、T 分期为 T1～2期原发性直肠癌患者淋巴结转移的相关影响因素；将上述原因纳入 Logistic 回归多因素分析中，结果表明肿瘤的分化程度、T 分期为 T1～2期原发性直肠癌患者淋巴结转移的独立影响因素。结论肿瘤的分化程度与 T 分期是 T1～2期原发性直肠癌患者淋巴结转移的独立影响因素，对于分化程度较高 T1的患者可以考虑行局部切除术。
目的：探討 T1～2期原髮性直腸癌患者淋巴結轉移的相關因素，為更好地確定直腸癌跼部切除的適應人群奠定科學基礎。方法選取在本院腫瘤外科住院行根治性手術的 T1～2期的原髮性直腸癌且治療的臨床資料完整的患者82例，將患者的性彆、年齡、腫瘤的直徑、腫瘤的組織類型、腫瘤的大體類型、分化程度、浸潤深度、T 分期以及術前癌胚抗原（CEA）水平等指標進行迴顧性分析。結果腫瘤的組織類型、腫瘤的大體類型、分化程度、浸潤深度、T 分期為 T1～2期原髮性直腸癌患者淋巴結轉移的相關影響因素；將上述原因納入 Logistic 迴歸多因素分析中，結果錶明腫瘤的分化程度、T 分期為 T1～2期原髮性直腸癌患者淋巴結轉移的獨立影響因素。結論腫瘤的分化程度與 T 分期是 T1～2期原髮性直腸癌患者淋巴結轉移的獨立影響因素，對于分化程度較高 T1的患者可以攷慮行跼部切除術。
목적：탐토 T1～2기원발성직장암환자림파결전이적상관인소，위경호지학정직장암국부절제적괄응인군전정과학기출。방법선취재본원종류외과주원행근치성수술적 T1～2기적원발성직장암차치료적림상자료완정적환자82례，장환자적성별、년령、종류적직경、종류적조직류형、종류적대체류형、분화정도、침윤심도、T 분기이급술전암배항원（CEA）수평등지표진행회고성분석。결과종류적조직류형、종류적대체류형、분화정도、침윤심도、T 분기위 T1～2기원발성직장암환자림파결전이적상관영향인소；장상술원인납입 Logistic 회귀다인소분석중，결과표명종류적분화정도、T 분기위 T1～2기원발성직장암환자림파결전이적독립영향인소。결론종류적분화정도여 T 분기시 T1～2기원발성직장암환자림파결전이적독립영향인소，대우분화정도교고 T1적환자가이고필행국부절제술。
Objective To investigate the related factors of the T1-2 primary patients with lymph node metastasis of rectal cancer, in order to better establish the scientific basis for defining suitable crowd for local excision of colorectal cancer. Methods 82 T1-2 patients with primary colorectal cancer and with complete clinical data in Surgical Oncology of the hospital underwent radical surgery, gender, age, tumor diameter, tumor histological type, tumor gross type, degree of differentiation, depth of invasion, T stage, preoperative carcinoembryonic antigen (CEA) levels and other indicators were analyzed retrospectively. Results The tumor tissue types, tumor gross type, degree of differentiation, depth of invasion, T staging were related factors in patients with primary colorectal cancer lymph node metastasis of T1-2; The Logistic regression multivariate analysis included the above reasons, the results showed tumor differentiation, T stage were independent predictors of lymph node metastasis in patients with primary colorectal cancer stage T1-2. Conclusions The degree of tumor differentiation and T stage were independent predictors of lymph node metastasis in patients with primary colorectal cancer T1-2 period, for a higher degree of differentiation may be considered in patients with T1 local excision.
