CAJ | 학술논문

目的：探讨肺表面活性物质治疗新生儿呼吸窘迫综合征的疗效。方法选取52例呼吸窘迫综合征患儿进行研究，随机分为观察组和对照组，各26例。观察组给予肺表面活性物质治疗，对照组给予常规治疗。结果观察组治疗2～3 h后皮肤颜色转红，TcSO2逐渐升高，6 h后PaO2及a/APO2的比值升高，而OI值降低。对照组治疗后PaO2及a/APO2的比值有所升高，OI降低。观察组机械通气及氧疗时间与对照组相比缩短，P＜0.05，差异具有统计学意义。结论肺表面活性物质治疗新生儿呼吸窘迫综合征疗效显著。
목적：탐토폐표면활성물질치료신생인호흡군박종합정적료효。방법선취52례호흡군박종합정환인진행연구，수궤분위관찰조화대조조，각26례。관찰조급여폐표면활성물질치료，대조조급여상규치료。결과관찰조치료2～3 h후피부안색전홍，TcSO2축점승고，6 h후PaO2급a/APO2적비치승고，이OI치강저。대조조치료후PaO2급a/APO2적비치유소승고，OI강저。관찰조궤계통기급양료시간여대조조상비축단，P＜0.05，차이구유통계학의의。결론폐표면활성물질치료신생인호흡군박종합정료효현저。
Objective To investigate the curative effect of pulmonary surfactant treatment neonatal respiratory distress dyndrome. Methods Selected 52 cases with respiratory distress syndrome, Randomly divided into the observation group and the control group, each group had 26 cases. The observation group received the treatment of pulmonary surfactant, The control group was treated with conventional therapy. Results After treatment, the skin color turned red and TcSO2 gradually increased in the observation group after treatment with 2 to 3 hours, After PaO2, the ratio of 6 h and a/APO2 increased obviously, and the OI value was signiifcantly decreased. The ratio of a/APO2 and PaO2 in control group was increased, and OI was not obvious. The observation group mechanical ventilation and oxygen therapy time was shorter than the control group. P<0.05, had difference statistically significance. Conclusion Pulmonary surfactant in treatment of neonatal respiratory distress syndrome has signiifcant curative effect.