临床医药实践
臨床醫藥實踐
림상의약실천
PROCEEDING OF CLINICAL MEDICINE
2015年
8期
604-607
,共4页
急性上呼吸道感染%小儿%抗生素%合理应用
急性上呼吸道感染%小兒%抗生素%閤理應用
급성상호흡도감염%소인%항생소%합리응용
acute upper respiratory infection%child%antibiotic%reasonable application
目的：比较单一抗生素与二联抗生素在治疗小儿急性细菌性上呼吸道感染的疗效、疗程及疾病转归等方面的差别。方法：将80例急性上呼吸道感染住院患儿随机分为两组，每组40例，治疗组使用氯唑西林钠，对照组使用青霉素钠联合头孢哌酮舒巴坦钠，两组均使用炎琥宁，进行对照观察。结果：治疗组有效率77.5%，对照组82.5%，经统计学分析，差异无统计学意义（P >0.05）。两组疗程、疾病转归及不良反应比较，差异无统计学意义。结论：使用一种抗生素治疗急性细菌性上呼吸道感染可以达到预期目的，联合静脉使用抗生素并不能加速症状、体征改善，不能显著提高有效率和改善预后，也不能缩短疗程。临床上应避免仅凭个人经验无依据多重应用抗生素。
目的：比較單一抗生素與二聯抗生素在治療小兒急性細菌性上呼吸道感染的療效、療程及疾病轉歸等方麵的差彆。方法：將80例急性上呼吸道感染住院患兒隨機分為兩組，每組40例，治療組使用氯唑西林鈉，對照組使用青黴素鈉聯閤頭孢哌酮舒巴坦鈉，兩組均使用炎琥寧，進行對照觀察。結果：治療組有效率77.5%，對照組82.5%，經統計學分析，差異無統計學意義（P >0.05）。兩組療程、疾病轉歸及不良反應比較，差異無統計學意義。結論：使用一種抗生素治療急性細菌性上呼吸道感染可以達到預期目的，聯閤靜脈使用抗生素併不能加速癥狀、體徵改善，不能顯著提高有效率和改善預後，也不能縮短療程。臨床上應避免僅憑箇人經驗無依據多重應用抗生素。
목적：비교단일항생소여이련항생소재치료소인급성세균성상호흡도감염적료효、료정급질병전귀등방면적차별。방법：장80례급성상호흡도감염주원환인수궤분위량조，매조40례，치료조사용록서서림납，대조조사용청매소납연합두포고동서파탄납，량조균사용염호저，진행대조관찰。결과：치료조유효솔77.5%，대조조82.5%，경통계학분석，차이무통계학의의（P >0.05）。량조료정、질병전귀급불량반응비교，차이무통계학의의。결론：사용일충항생소치료급성세균성상호흡도감염가이체도예기목적，연합정맥사용항생소병불능가속증상、체정개선，불능현저제고유효솔화개선예후，야불능축단료정。림상상응피면부빙개인경험무의거다중응용항생소。
Objective:Compared the differences in clinical efficacy,disease course and disease outcome between single and joint use of antibiotics in treatment of children with acute bacterial upper respiratory infection. Methods:Eighty cases of hospitalized children with acute bacterial upper respiratory infection were divided randomly into two groups,40 cases of treat-ment group were treated with intravenous cloxacillin sodium,40 cases of control group were treated with intravenous penicillin sodium and cefoperazone and sulbactam sodium,all cases were treated with potassium sodium dehydroandroan drographolide succinate for injection,a parallel comparison observation was carried out between two groups. Results:After therapy,there were no significant differences in effective rates beween reatment group(77. 5% )and control group(82. 5% )(P > 0. 05). Both groups were also similar in disease course,disease outcome and adverse reactions. Conclusion:Use of single antibiotic treatment of acute bacterial upper respiratory infections can achieve the intended objective,joint use of antibiotics can not accelerate to improve the symptoms and signs,can not increase the significant effective rates,can not improve the disease outcome,nor short-ened course. Multiple use of antibiotics should be avoided only by personal experiences without clinical evidence.
