CAJ | 학술논문

目的：观察尿激酶联合抗结核药胸腔内注入对结核性包裹性胸腔积液预后的疗效影响。方法将72例结核性包裹性胸腔积液病人，在常规规范抗痨的基础上随机分为治疗及对照组，每组各36例，对照组行常规胸腔彩超引导胸穿，治疗组行胸穿外，加胸腔内注入尿激酶、异烟肼、利福平。比较两组的胸水消失时间，住院治疗时间，治疗后胸膜增厚及粘连程度，肺功能改善情况。结果胸腔内注入尿激酶联合抗结核药物治疗结核性包裹性积液。结论尿激酶联合抗结核药胸腔内注入对胸水消失时间、明显减轻胸膜肥厚，对胸膜粘连及其改善肺功能有明显的疗效。
목적：관찰뇨격매연합항결핵약흉강내주입대결핵성포과성흉강적액예후적료효영향。방법장72례결핵성포과성흉강적액병인，재상규규범항로적기출상수궤분위치료급대조조，매조각36례，대조조행상규흉강채초인도흉천，치료조행흉천외，가흉강내주입뇨격매、이연정、리복평。비교량조적흉수소실시간，주원치료시간，치료후흉막증후급점련정도，폐공능개선정황。결과흉강내주입뇨격매연합항결핵약물치료결핵성포과성적액。결론뇨격매연합항결핵약흉강내주입대흉수소실시간、명현감경흉막비후，대흉막점련급기개선폐공능유명현적료효。
Objective To investigate the effect of intrapleural injection of urokinase and anti - TB on curing tuberculous encap-sulated pleural effusion. Methods 72patients suffering from tuberculousencapsulated pleural effusion underwent regular anti - TB treatment and were randomly divided into Treatment and Control group,each group 36 cases. The control group underwent routine chest ultrasound guided thoracentesis,and the Treatment group plus intrapleural injection of urokinase,isoniazid and rifampicin be-sides routine thoracentesis. To measure the pleural effusion disappear time,hospitalization time,and pleural thickening and adhesion, lung function of the two groups before and after treatment. Results The method that intrapleural injection ofurokinase combined anti -TB to cure tuberculous encapsulated pleural effusion has curative effect on shortening pleural effusion disappear time. Conclusion re-ducing pleural thickening and improving pleural adhesions and lung function.