CAJ | 학술논문

目的研究胶囊内镜对克罗恩病的诊断、指导治疗及预后的价值.方法对4例确诊和22例临床拟诊的克罗恩病患者行胶囊内镜检查,前瞻性分析检查后发现克罗恩病病变位置、指导治疗药物的变化,通过随访1年了解患者疾病活动的变化,分析治疗是否有效.结果胶囊内镜检查后发现小肠病变累及率由57.7％变为80.8％,而对症治疗减少,激素、免疫抑制剂应用明显增加.通过1年随访,22例拟诊克罗恩病患者中12例改为确诊,2例被排除.C反应蛋白(CRP)、克罗恩病活动指数(CDAI)、炎症性肠病生存质量问卷(IBDQ)、刘易斯评分(LS)基线值及复查数值分别进行方差分析,P值均＜0.05,即治疗有效.结论胶囊内镜检查有益于克罗恩病的确诊、指导治疗及预后.
목적 연구효낭내경대극라은병적진단、지도치료급예후적개치.방법 대4례학진화22례림상의진적극라은병환자행효낭내경검사,전첨성분석검사후발현극라은병병변위치、지도치료약물적변화,통과수방1년료해환자질병활동적변화,분석치료시부유효.결과 효낭내경검사후발현소장병변루급솔유57.7％변위80.8％,이대증치료감소,격소、면역억제제응용명현증가.통과1년수방,22례의진극라은병환자중12례개위학진,2례피배제.C반응단백(CRP)、극라은병활동지수(CDAI)、염증성장병생존질량문권(IBDQ)、류역사평분(LS)기선치급복사수치분별진행방차분석,P치균＜0.05,즉치료유효.결론 효낭내경검사유익우극라은병적학진、지도치료급예후.
Objective To evaluate the value of capsule endoscopy (CE)in diagnosis,management and prognosis of crohn's disease(CD).Methods Four diagnosed CD patients and 22 patients with suspected CD underwent CE.The lesion location and drug therapy were analysed prospectively.Follow-up of one year was conducted to evaluate the disease and the effectiveness of therapy.Results There was an increase in detection rate of small bowel involvement,namely,from 57.7％ to 80.8％,and a decrease in symptomatic treatment and an increase in medication of hormone and immune inhibitors.After the follow-up of 12 months,12 suspected CD patients were confirmed,and 2 patients were excluded.Variance analysis of CRP,CDAI,IBDQ and LS were conducted by repeated measures (P ＜ 0.05) and that meant the therapy was effective.Conclusion CE is useful for diagnosis,treatment and prognosis of CD.