中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2015年
20期
127-129
,共3页
卡前列素氨丁三醇%宫缩乏力%产后出血
卡前列素氨丁三醇%宮縮乏力%產後齣血
잡전렬소안정삼순%궁축핍력%산후출혈
Carboprost tromethamine%Uerine inertia%Postpartum hemorrhage
目的：研究卡前列素氨丁三醇防治产妇产后出血的临床效果。方法2011年1月~2014年1月，选择90例存在宫缩乏力性产后出血因素的产妇进行研究，按随机数χ表法分为试验组(45例)与对照组(45例)，两组产妇在胎儿娩出后均静脉滴注20 U缩宫素，在此基础上，试验组产妇宫肌注射或臀肌注射250μg卡前列素氨丁三醇，对照组产妇宫肌注射或臀肌注射20 U缩宫素。经处理后，比较两组产妇的产后2、24 h出血量，产后出血及不良反应发生情况。结果试验组产后2、24 h出血量及产后24 h血红蛋白下降值均显著少于对照组(P<0.05)；试验组的产后出血发生率为11.1%，明显低于对照组(31.1%)，两组比较，差异有统计学意义(χ2=5.4040，P=0.0201)；试验组的不良反应发生率为13.3%，对照组为8.9%，两组比较，差异无统计学意义(χ2=0.4500，P=0.5023)。结论卡前列素氨丁三醇防治产妇产后出血的效果良好，安全性高，值得临床推广应用。
目的：研究卡前列素氨丁三醇防治產婦產後齣血的臨床效果。方法2011年1月~2014年1月，選擇90例存在宮縮乏力性產後齣血因素的產婦進行研究，按隨機數χ錶法分為試驗組(45例)與對照組(45例)，兩組產婦在胎兒娩齣後均靜脈滴註20 U縮宮素，在此基礎上，試驗組產婦宮肌註射或臀肌註射250μg卡前列素氨丁三醇，對照組產婦宮肌註射或臀肌註射20 U縮宮素。經處理後，比較兩組產婦的產後2、24 h齣血量，產後齣血及不良反應髮生情況。結果試驗組產後2、24 h齣血量及產後24 h血紅蛋白下降值均顯著少于對照組(P<0.05)；試驗組的產後齣血髮生率為11.1%，明顯低于對照組(31.1%)，兩組比較，差異有統計學意義(χ2=5.4040，P=0.0201)；試驗組的不良反應髮生率為13.3%，對照組為8.9%，兩組比較，差異無統計學意義(χ2=0.4500，P=0.5023)。結論卡前列素氨丁三醇防治產婦產後齣血的效果良好，安全性高，值得臨床推廣應用。
목적：연구잡전렬소안정삼순방치산부산후출혈적림상효과。방법2011년1월~2014년1월，선택90례존재궁축핍력성산후출혈인소적산부진행연구，안수궤수χ표법분위시험조(45례)여대조조(45례)，량조산부재태인면출후균정맥적주20 U축궁소，재차기출상，시험조산부궁기주사혹둔기주사250μg잡전렬소안정삼순，대조조산부궁기주사혹둔기주사20 U축궁소。경처리후，비교량조산부적산후2、24 h출혈량，산후출혈급불량반응발생정황。결과시험조산후2、24 h출혈량급산후24 h혈홍단백하강치균현저소우대조조(P<0.05)；시험조적산후출혈발생솔위11.1%，명현저우대조조(31.1%)，량조비교，차이유통계학의의(χ2=5.4040，P=0.0201)；시험조적불량반응발생솔위13.3%，대조조위8.9%，량조비교，차이무통계학의의(χ2=0.4500，P=0.5023)。결론잡전렬소안정삼순방치산부산후출혈적효과량호，안전성고，치득림상추엄응용。
Objective To study the clinical effect preventing and treating of postpartum hemorrhage of puerpera. Methods From January 2011 to January 2014,90 puerperae with postpartum hemorrhage due to uterine inertia were selected and evenly divided into experimental group and control group by random number table method.After delivery, 20 U oxytocin was applied by intravenous drip in both groups.On the basis,250 μg carboprost tromethamine was injected by uterus muscle or gluteus in experimental group.In control group,20 U oxytocin was injected by uterus muscle or gluteus.After treatment,the amount of bleeding after 2 hours and 24 hours delivery,occurrence of postpartum hemorrhage and adverse reaction between two groups were compared. Results Amount of bleeding after 2 hours and 24 hours,and the decreased value of hemoglobin after 24 hours delivery was greatly lower than that in control group respectively (P<0.05).The incidence rate of postpartum hemorrhage in experimental group (11.1%) was lower in comparison with that in control group (31.1%) with a statistical difference (χ2=5.4040,P=0.0201).The incidence rate of adverse reaction in experimental group (13.3%),while it was 8.9% in control group,and there was no statistical difference between two groups (χ2=0.4500,P=0.5023). Conclusion Carboprost tromethamine can obtain a good effect on preventing and treating of postpartum hemorrhage of puerpera with high safety,which is worthy of clinical promotion and application.
