CAJ | 학술논문

目的：探讨大深度饱和潜水对潜水员血液生化指标的影响，并分析产生影响的可能原因，为制定大深度饱和潜水时潜水员身体健康的保障措施提供依据。方法4名健康男性潜水员参加模拟480 m氦氧饱和潜水，检测潜水员实验前后1 d内血清总蛋白（ total protein，TP）、白蛋白（ albumin， ALB）、球蛋白（globulin，GLB）、总胆固醇（total cholesterol，TC）、三酰甘油（triglyceride，TG）、葡萄糖（glucose，Glu）、肌酐（creatinine，Cr）、尿素氮（blood urea nitrogen，BUN）、尿酸（uric acid，UA）、免疫球蛋白IgA、IgG、IgM、补体C3、C4水平及血清电解质钾（ K＋）、钠（ Na＋）、镁（ Mg2＋）、钙（ Ca2＋）、铁（ Fe3＋）、氯（Cl －）水平。结果潜水员大深度饱和潜水出舱后血 UA 为（387．75±35．37）μmol／L，较入舱前（482．75±75．20）μmol／L下降（P＜0．05）；出舱后血K＋（4．00±0．14）mmol／L，较入舱前（4．30±0．29） mmol／L下降（P＜0．05）；出舱后血IgA（2．36±0．62）g／L ，较入舱前（1．92±0．27）g／L上升（P＜0．05），而补体C3出舱后为（1．02±0．11）g／L，较入舱前（1．20±0．26）g／L下降（P＜0．05）。结论大深度饱和潜水对潜水员某些血液生化指标有一定影响，应进一步加强监控，并改进保障措施，以保障其身体健康。
목적：탐토대심도포화잠수대잠수원혈액생화지표적영향，병분석산생영향적가능원인，위제정대심도포화잠수시잠수원신체건강적보장조시제공의거。방법4명건강남성잠수원삼가모의480 m양양포화잠수，검측잠수원실험전후1 d내혈청총단백（ total protein，TP）、백단백（ albumin， ALB）、구단백（globulin，GLB）、총담고순（total cholesterol，TC）、삼선감유（triglyceride，TG）、포도당（glucose，Glu）、기항（creatinine，Cr）、뇨소담（blood urea nitrogen，BUN）、뇨산（uric acid，UA）、면역구단백IgA、IgG、IgM、보체C3、C4수평급혈청전해질갑（ K＋）、납（ Na＋）、미（ Mg2＋）、개（ Ca2＋）、철（ Fe3＋）、록（Cl －）수평。결과잠수원대심도포화잠수출창후혈 UA 위（387．75±35．37）μmol／L，교입창전（482．75±75．20）μmol／L하강（P＜0．05）；출창후혈K＋（4．00±0．14）mmol／L，교입창전（4．30±0．29） mmol／L하강（P＜0．05）；출창후혈IgA（2．36±0．62）g／L ，교입창전（1．92±0．27）g／L상승（P＜0．05），이보체C3출창후위（1．02±0．11）g／L，교입창전（1．20±0．26）g／L하강（P＜0．05）。결론대심도포화잠수대잠수원모사혈액생화지표유일정영향，응진일보가강감공，병개진보장조시，이보장기신체건강。
Objective To explore the effects of deep saturation diving on blood biochemical indices in divers and to analyze the possible causes involved , so as to provide theoretical evidence for the development of medical support profile for the health promotion of divers .Methods Four healthy male divers participated in the 4.9 MPa (480 m) simulated saturation dive.The serum levels of total protein (TP), albumin (ALB), Globulin (GLB), total cholesterol (TC), triglyceride (TG), glucose (Glu), Creatinine (Cr), blood urea nitrogen (BUN), uric acid (UA), immunoglobulin IgA, IgG, IgM, complement C3, C4 were detected by Olympus 2 700 automatic biochemical analyzer .In addition, serum electrolytes potassium ( K+), sodium ( Na+) , magnesium ( Mg2+) , calcium ( Ca2+) , Iron ( Fe3+) and chlorine ( Cl-) were determined by Toshiba 40FR automatic biochemical analyzer .Results Serum UA level (387.75 ±35.37) μmol/L of the divers after they came out of the chamber upon completion of the deep saturation dive was obviously lower than that before the entrance into the chamber (482.75 ±75.20) μmol/L (P<0.05).Serum K +level of the divers (4.00 ± 0.14) mmol /L after they came out of the chamber was markedly lower than that before entrance into the chamber(4.30 ±0.29)mmol/L (P <0.05).IgA level of the divers after they came out of the chamber (2.36 ±0.62)g/L was obviously higher than that before entrance into the chamber (1.92 ±0.72)g/L(P<0.05), while C3 level of the divers after exposure (1.02 ±0.11) g/L was lower than that before exposure (1.20 ±0.26) g/L ( P <0.05).Conclusions Deep saturation dive had certain effects on the serum biochemical indices of the divers .Monitoring on the biochemical indices should be enhanced and medical support measures be improved , so as to ensure the health of divers .