CAJ | 학술논문

作为重要的含氮杂环化合物厄洛替尼，近年来吸引了越来越多不同领域化学家的关注，也出现了很多不同的合成方法，但是很多方法都存在这样或那样的问题。为了方便今后合成研究需要，为了降低成本，减少环境污染，提高产率，一些合成中的新发现、新策略、新技术相继涌现，从所用的原料、合成路线、工艺条件进行综述，并对该化合物的合成前景进行展望。
작위중요적함담잡배화합물액락체니，근년래흡인료월래월다불동영역화학가적관주，야출현료흔다불동적합성방법，단시흔다방법도존재저양혹나양적문제。위료방편금후합성연구수요，위료강저성본，감소배경오염，제고산솔，일사합성중적신발현、신책략、신기술상계용현，종소용적원료、합성로선、공예조건진행종술，병대해화합물적합성전경진행전망。
Abstact:Erlotinib, an important nitrogen heterocyclic compounds, attracts the attention of more and more chemists from different fields.Therefore, various synthesis methods arise, though some of which still have some problems.For convenience of future research, from the perspective of lowering the cost, reducing environmental pollution, as well as increasing the production rate, some new discoveries, new strategies, and new techniques emerged one after another. Hence, the raw materials used, synthetic route and technological conditions were summarized. The future of the compounds synthesis was prospected as well.