CAJ | 학술논문

目的：探讨江苏省阜宁县50岁及以上人群中前房角关闭的患病率特征。方法于2010年3～5月，采取整群随机抽样法在阜宁县调查了5202例，应用Van Herick法对受检人群进行周边前房深度检查初筛，对其中周边前房深度≤1/3角膜厚度者进行前房角镜检查，确定为解剖的窄前房角者再进行明、暗光线下超声活体显微镜（UBM）检查，分别观察受检眼上方、颞上方、颞侧、颞下方、下方、鼻下方、鼻侧和鼻上方8个检查部位有无前房角关闭，评估具有解剖的窄前房角患眼前房角关闭率。从UBM图像中测量前房角开放距离。明、暗光线下前房角关闭率比较采用配对χ2检验，前房角开放距离的比较采用配对t检验。结果经Van Herick法初筛出347例浅前房患者，完成全部检查的共有243例（484只眼）患者。以受检眼计算，在明、暗光线下UBM检查发现的前房角关闭率分别为24.0%和69.6%，显示暗光线下前房角关闭率明显增高，两者间差异有统计学意义（χ2=204.36，P<0.001）。明光线下以鼻上方最高，为14.3%，暗光线下以上方的前房角关闭率最高，为42.8%。明或暗光线下，8个检查部位之间前房角开放距离的差异均有统计学意义（t=6.039，6.883，11.612，11.157，4.732，6.798，5.156，4.071；P<0.001）。按受检者暗光线UBM检查下前房角关闭率81.07%估计，阜宁县50岁及以上人群前房角关闭率为5.40%（95%CI：4.80%～6.05%）。结论本调查人群的前房角关闭患病率高于以往调查结果，这可能与本研究采取的检查方法，即UBM暗光线下检查前房角能够早期筛查前房角关闭患者有关。（中华眼科杂志，2015，51：487-492）
목적：탐토강소성부저현50세급이상인군중전방각관폐적환병솔특정。방법우2010년3～5월，채취정군수궤추양법재부저현조사료5202례，응용Van Herick법대수검인군진행주변전방심도검사초사，대기중주변전방심도≤1/3각막후도자진행전방각경검사，학정위해부적착전방각자재진행명、암광선하초성활체현미경（UBM）검사，분별관찰수검안상방、섭상방、섭측、섭하방、하방、비하방、비측화비상방8개검사부위유무전방각관폐，평고구유해부적착전방각환안전방각관폐솔。종UBM도상중측량전방각개방거리。명、암광선하전방각관폐솔비교채용배대χ2검험，전방각개방거리적비교채용배대t검험。결과경Van Herick법초사출347례천전방환자，완성전부검사적공유243례（484지안）환자。이수검안계산，재명、암광선하UBM검사발현적전방각관폐솔분별위24.0%화69.6%，현시암광선하전방각관폐솔명현증고，량자간차이유통계학의의（χ2=204.36，P<0.001）。명광선하이비상방최고，위14.3%，암광선하이상방적전방각관폐솔최고，위42.8%。명혹암광선하，8개검사부위지간전방각개방거리적차이균유통계학의의（t=6.039，6.883，11.612，11.157，4.732，6.798，5.156，4.071；P<0.001）。안수검자암광선UBM검사하전방각관폐솔81.07%고계，부저현50세급이상인군전방각관폐솔위5.40%（95%CI：4.80%～6.05%）。결론본조사인군적전방각관폐환병솔고우이왕조사결과，저가능여본연구채취적검사방법，즉UBM암광선하검사전방각능구조기사사전방각관폐환자유관。（중화안과잡지，2015，51：487-492）
Objective The purpose of the study is to determine the prevalence of appositional angle closure in persons aged 50 or above in Funing County. Methods Cluster sampling randomly selected residents in Funing County aged 50 years or above. From March to May 2010, 484 eyes of 243 patients with the shallow peripheral anterior chamber and the anatomic narrow chamber angle, which was determined by Van Herick technique and gonioscopy, were collected from 5202 individuals. The presence of appositional angle closure and the angle-opening distance(AOD) was determined with photopic and scotopic ultrasound biomicroscopy(UBM) in eight positions. Paired χ2 test and paired t test(SPSS 17.0) were used to determine any significant differences at P<0.05. Results The prevalence of appositional angle closure was found at least one position in 337 eyes(69.6%) by scotopic UBM and in 116 eyes(24.0%) by photopic UBM. The prevalence of appositional angle closure was significantly higher by scotopic UBM than by photopic UBM(χ2=204.36, P<0.001 respectively), and was the highest in superior quadrant. The AOD varied significantly among the eight positions and was significantly narrower by scotopic UBM than by photopic UBM (t=6.039, 6.883, 11.612, 11.157, 4.732, 6.798, 5.156, 4.071; P<0.001). Since 197 persons(81.07%) were found anterior angle closure by scotopic UBM, we estimated the prevalence of appositional angle closure was 5.40 %(95%CI: 4.80%-6.05%)among adults aged 50 or above in Funing County. Conclusions The prevalence of appositional angle closure was higher than previous surveys, the possible reason is that scotopic UBM could find early appositional angle closure more preferably.