中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2015年
7期
624-626
,共3页
咳嗽变异性哮喘%孟鲁司特钠%三拗片%风寒束肺
咳嗽變異性哮喘%孟魯司特鈉%三拗片%風寒束肺
해수변이성효천%맹로사특납%삼요편%풍한속폐
Cough variant asthma%Montelukast tables%San'ao Tables%Cold beam lung card
目的 观察孟鲁司特钠联合三拗片治疗咳嗽变异性哮喘(CVA)(风寒束肺证)的临床效果.方法 选择符合CVA的西医诊断标准且中医辨证为风寒束肺证患者89例,应用随机数字表法分为治疗组45例(失访3例,最终为42例),对照组44例(失访4例,最终为40例).对照组应用孟鲁司特钠片治疗,治疗组应用孟鲁司特钠片联合三拗片治疗.两组疗程均为14d.测定并比较治疗前后中医证候和主要症状的变化.结果 治疗组改善CVA患者中医证候[有效率(90.48％,38/42)、咳嗽程度总有效率(85.71％,36/42)、频度总有效率(90.48％,38/42)、咯痰总有效率(85.71％,36/42)、咽痒总有效率(80.95％,34/42)、恶寒总有效率(76.19％,32/42)]的临床疗效均优于对照组[70.00％ (28/40)、62.50％(25/40)、70.00％(28/40)、55.00％ (22/40)、52.50％(21/40)、25.00％(10/40)],差异有统计学意义(x2值分别为14.046、14.046、13.923、23.104、17.729、17.729,P＜0.05或P＜0.01).结论 孟鲁司特钠联合三拗片在改善CVA患者中医证候、咳嗽、咯痰等临床症状方面优于单纯孟鲁司特钠片治疗.
目的 觀察孟魯司特鈉聯閤三拗片治療咳嗽變異性哮喘(CVA)(風寒束肺證)的臨床效果.方法 選擇符閤CVA的西醫診斷標準且中醫辨證為風寒束肺證患者89例,應用隨機數字錶法分為治療組45例(失訪3例,最終為42例),對照組44例(失訪4例,最終為40例).對照組應用孟魯司特鈉片治療,治療組應用孟魯司特鈉片聯閤三拗片治療.兩組療程均為14d.測定併比較治療前後中醫證候和主要癥狀的變化.結果 治療組改善CVA患者中醫證候[有效率(90.48％,38/42)、咳嗽程度總有效率(85.71％,36/42)、頻度總有效率(90.48％,38/42)、咯痰總有效率(85.71％,36/42)、嚥癢總有效率(80.95％,34/42)、噁寒總有效率(76.19％,32/42)]的臨床療效均優于對照組[70.00％ (28/40)、62.50％(25/40)、70.00％(28/40)、55.00％ (22/40)、52.50％(21/40)、25.00％(10/40)],差異有統計學意義(x2值分彆為14.046、14.046、13.923、23.104、17.729、17.729,P＜0.05或P＜0.01).結論 孟魯司特鈉聯閤三拗片在改善CVA患者中醫證候、咳嗽、咯痰等臨床癥狀方麵優于單純孟魯司特鈉片治療.
목적 관찰맹로사특납연합삼요편치료해수변이성효천(CVA)(풍한속폐증)적림상효과.방법 선택부합CVA적서의진단표준차중의변증위풍한속폐증환자89례,응용수궤수자표법분위치료조45례(실방3례,최종위42례),대조조44례(실방4례,최종위40례).대조조응용맹로사특납편치료,치료조응용맹로사특납편연합삼요편치료.량조료정균위14d.측정병비교치료전후중의증후화주요증상적변화.결과 치료조개선CVA환자중의증후[유효솔(90.48％,38/42)、해수정도총유효솔(85.71％,36/42)、빈도총유효솔(90.48％,38/42)、각담총유효솔(85.71％,36/42)、인양총유효솔(80.95％,34/42)、악한총유효솔(76.19％,32/42)]적림상료효균우우대조조[70.00％ (28/40)、62.50％(25/40)、70.00％(28/40)、55.00％ (22/40)、52.50％(21/40)、25.00％(10/40)],차이유통계학의의(x2치분별위14.046、14.046、13.923、23.104、17.729、17.729,P＜0.05혹P＜0.01).결론 맹로사특납연합삼요편재개선CVA환자중의증후、해수、각담등림상증상방면우우단순맹로사특납편치료.
Objective To observe the Clinical effects on Sanao tables combined with Montelukast Tables for cough variant asthma (CVA) (cold beam lung card).Methods Eighty-nine cases of sydrome differentiation (cold beam lung card) complied with CVA diagnostic criteria were randomly divided into treatment group (45 cases,3 cases were lost) and control group(44 cases,4 cases were lost)).The treatment group was given oral San'ao tables combined with Montelukast tables,and the control group was given oral Montelukast tables.The course of treatment were all 14 days.Chinese medical syndrome,cardinal symptom and airway reactivity effects were determined and compared at pretherapy.Results Clinical effects of Chinese medical syndrome (effective rate (90.48％,38/42),cough severity (85.71％,36/42),frequency (90.48％,38/42),cough up phlegm (85.71％,36/42),pharyngeal itching (80.95％,4/42) and aversion to cold (76.19％,32/ 42)) in treatment group were all superior to control group (70.00％ (28/40),62.50％ (25/40),70.00％ (28/ 40),55.00％ (22/40),52.50％ (21/40),25.00％ (10/40)).The differences were statistical significance (x2=14.046,14.046,13.923,23.104,17.729,17.729;P＜0.05 or P＜0.01).Conclusion Clinical effects of San' ao tables combined with Montelukast tables on CVA is superior to Montelukast tables.
