国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2015年
14期
1048-1051
,共4页
重症肺炎%全身炎症反应综合征%血乳酸%氧合指数%C反应蛋白
重癥肺炎%全身炎癥反應綜閤徵%血乳痠%氧閤指數%C反應蛋白
중증폐염%전신염증반응종합정%혈유산%양합지수%C반응단백
Severe pneumonia%Systemic inflammation response syndrome%Blood lactic acid%Oxygenation index%C-reactive protein
目的 回顾性分析重症肺炎患者动态监测动脉血乳酸、氧合指数及C反应蛋白(CRP)的变化.方法 34例重症肺炎患者中,26例存活(存活组),8例死亡(死亡组),分析比较两组动脉血乳酸、氧合指数及C反应蛋白的变化;结合急性生理学、年龄及既往疾病评估预后系统(APACHEⅡ)评分,分析其在疾病转归与预后的价值.结果 存活组血乳酸水平明显低于死亡组,其血乳酸在入院治疗12～24 h迅速降低到正常水平,而死亡组血乳酸呈持续高水平状态;存活组患者的氧合指数明显高于死亡组,且维持在正常水平,而死亡组氧合指数低于正常且持续下降.死亡组C反应蛋白72 h内无明显下降,较存活组明显升高(P ＜0.05).APACHEⅡ评分与血乳酸浓度呈正相关(r=0.656,P＜0.05).结论 重症肺炎患者动态监测动脉血乳酸、氧合指数及C反应蛋白水平在评估疗效、判断预后中具有重要意义.
目的 迴顧性分析重癥肺炎患者動態鑑測動脈血乳痠、氧閤指數及C反應蛋白(CRP)的變化.方法 34例重癥肺炎患者中,26例存活(存活組),8例死亡(死亡組),分析比較兩組動脈血乳痠、氧閤指數及C反應蛋白的變化;結閤急性生理學、年齡及既往疾病評估預後繫統(APACHEⅡ)評分,分析其在疾病轉歸與預後的價值.結果 存活組血乳痠水平明顯低于死亡組,其血乳痠在入院治療12～24 h迅速降低到正常水平,而死亡組血乳痠呈持續高水平狀態;存活組患者的氧閤指數明顯高于死亡組,且維持在正常水平,而死亡組氧閤指數低于正常且持續下降.死亡組C反應蛋白72 h內無明顯下降,較存活組明顯升高(P ＜0.05).APACHEⅡ評分與血乳痠濃度呈正相關(r=0.656,P＜0.05).結論 重癥肺炎患者動態鑑測動脈血乳痠、氧閤指數及C反應蛋白水平在評估療效、判斷預後中具有重要意義.
목적 회고성분석중증폐염환자동태감측동맥혈유산、양합지수급C반응단백(CRP)적변화.방법 34례중증폐염환자중,26례존활(존활조),8례사망(사망조),분석비교량조동맥혈유산、양합지수급C반응단백적변화;결합급성생이학、년령급기왕질병평고예후계통(APACHEⅡ)평분,분석기재질병전귀여예후적개치.결과 존활조혈유산수평명현저우사망조,기혈유산재입원치료12～24 h신속강저도정상수평,이사망조혈유산정지속고수평상태;존활조환자적양합지수명현고우사망조,차유지재정상수평,이사망조양합지수저우정상차지속하강.사망조C반응단백72 h내무명현하강,교존활조명현승고(P ＜0.05).APACHEⅡ평분여혈유산농도정정상관(r=0.656,P＜0.05).결론 중증폐염환자동태감측동맥혈유산、양합지수급C반응단백수평재평고료효、판단예후중구유중요의의.
Objective To analyze the clinical significance of dynamic monitoring blood lactic acid,oxygenation index and C-reactive protein (CRP) in patients with severe pneumonia.Methods The clinical data of 34 patients with severe pneumonia were collected.According to clinical outcomes,the patients were divided into survival group (n =26) and dead group (n =8).The blood lactic acid,oxygenation index,CRP and APACHE Ⅱ score were retrospectively analyzed in order to explore the clinical significance of these indexes for prognosis of the patients.Results There was no difference in age,sex,the initial concentrations of blood lactic acid,CRP and APACHE Ⅱ score at admission to ICU.However,blood lactic acid level decreased to the normal level within 12-24 hours after treatment in the survival group while it maintained higher level in the dead group even at 72nd hour after treatment.Oxygenation index in the survival group was significantly higher than that in the dead group.Moreover,oxygenation index was maintained in normal level in the survival group while it was below normal level and continued to decline.There was a positive correlation between blood lactic acid and APACHE Ⅱ score (r =0.656,P ＜ 0.05).Conclusions The dynamic monitoring levels of blood lactic acid,oxygenation index and CRP in patients with severe pneumonia can not only evaluate the therapeutic efficiency,but also estimate the prognosis for patients with severe pneumonia.
