CAJ | 학술논문

目的：探讨孟鲁司特辅助治疗反复发作性小儿过敏性紫癜临床疗效及安全性。方法选取我院收治的反复发作性过敏性紫癜患儿102例，随机分为观察组和对照组，两组均为51例。对照组以常规疗法进行治疗，观察组在常规疗法的基础上加服孟鲁司特咀嚼片，比较两组治疗效果及不良反应。结果4周后，对照组总有效率为70．6％，观察组总有效率为94．1％，两组在治疗期间均无明显不良反应出现。结论孟鲁司特能够显著提高常规疗法对反复发作性小儿过敏性紫癜临床疗效，并无不良反应发生。
목적：탐토맹로사특보조치료반복발작성소인과민성자전림상료효급안전성。방법선취아원수치적반복발작성과민성자전환인102례，수궤분위관찰조화대조조，량조균위51례。대조조이상규요법진행치료，관찰조재상규요법적기출상가복맹로사특저작편，비교량조치료효과급불량반응。결과4주후，대조조총유효솔위70．6％，관찰조총유효솔위94．1％，량조재치료기간균무명현불량반응출현。결론맹로사특능구현저제고상규요법대반복발작성소인과민성자전림상료효，병무불량반응발생。
OBJECTIVE To investigate the curative effect of montelukast on adjuvant treating of repeated relap-singpediatricallergicpurpura.METHODS 102casesofrepeatedrelapsingpediatricallergicpurpurawererandom-ly divided into two groups ,control group (51 cases) using routine treatment and observation group (51 cases) using routine treatment and montelukast chewable tablet .The treatment effect and untoward effect were compared in two groups.RESULTS After 4 weeks,the total effective rate was 70.6% in control group and 94.1% in observation group.There was no adverse drug reaction occurred during the treatment .CONCLUSION Montelukast can signifi-cantly improve the effect of routine treatment on the repeated relapsing pediatric allergic purpura without adverse drug reaction.