上海医药
上海醫藥
상해의약
SHANGHAI MEDICAL & PHARMACEUTICAL JOURNAL
2015年
15期
68-72,75
,共6页
甘油磷脂酰胆碱%生物特性%制备%分离纯化
甘油燐脂酰膽堿%生物特性%製備%分離純化
감유린지선담감%생물특성%제비%분리순화
L-a-glycerylphosphorylcholine%biological characteristics%preparation%synthesis and separation
人口老龄化是当今社会的发展趋势，老年痴呆症已成为危及老年人生命的“第四大杀手”，抗痴呆药物的研究是近年来的热点。本文对治疗阿尔茨海默病等痴呆症的药物——L-a-甘油磷脂酰胆碱作一介绍，包括近年来的市场状况及前景、临床应用、分离及其纯化方法等。以进一步促进 L-a-甘油磷脂酰胆碱类药物的制备与应用，填补国内该类药物制备的空白。
人口老齡化是噹今社會的髮展趨勢，老年癡呆癥已成為危及老年人生命的“第四大殺手”，抗癡呆藥物的研究是近年來的熱點。本文對治療阿爾茨海默病等癡呆癥的藥物——L-a-甘油燐脂酰膽堿作一介紹，包括近年來的市場狀況及前景、臨床應用、分離及其純化方法等。以進一步促進 L-a-甘油燐脂酰膽堿類藥物的製備與應用，填補國內該類藥物製備的空白。
인구노령화시당금사회적발전추세，노년치태증이성위위급노년인생명적“제사대살수”，항치태약물적연구시근년래적열점。본문대치료아이자해묵병등치태증적약물——L-a-감유린지선담감작일개소，포괄근년래적시장상황급전경、림상응용、분리급기순화방법등。이진일보촉진 L-a-감유린지선담감류약물적제비여응용，전보국내해류약물제비적공백。
Alzheimer’s disease has been become “the fourth killer” threatening the life of the elderly due to the trend of population aging in today’s society, so the research and development of anti-dementia drugs have been a hot point currently. This article introduces L-a-glycerylphosphorylcholine, one of the anti-dementia drugs for the treatment of Alzheimer’s disease, including its market state and prospects, clinical application, preparation and purification and so on so as to further promote the preparation and application of L-a-glycerylphosphorylcholine –like drugs and fill in the gaps in home-made such products.
