CAJ | 학술논문

目的：分析CADASIL的临床特点，以便早期诊治。方法对3例确诊为CADASIL的患者进行回顾性研究。结果 CADASIL表现为皮质下缺血事件，并导致进行性痴呆伴假性球麻痹、严重情感障碍，而最早的临床表现可为有先兆的偏头痛。结论当患者有TIA或卒中、严重情感障碍、伴先兆的偏头痛、痴呆等表现，MRI或CT显示皮质下白质、基底节广泛异常改变时，要考虑CADASIL的诊断。
목적：분석CADASIL적림상특점，이편조기진치。방법대3례학진위CADASIL적환자진행회고성연구。결과 CADASIL표현위피질하결혈사건，병도치진행성치태반가성구마비、엄중정감장애，이최조적림상표현가위유선조적편두통。결론당환자유TIA혹졸중、엄중정감장애、반선조적편두통、치태등표현，MRI혹CT현시피질하백질、기저절엄범이상개변시，요고필CADASIL적진단。
Objective To analyze the clinical characteristics of CADASIL for early diagnosis and treatment. Methods 3 cases of diagnosed with CADASIL patients were retrospectively studied. Results CADASIL manifestations of subcortical ischemic events, and cause of dementia patients with pseudobulbar palsy, severe mood disorders, and the early clinical manifestations can be for migraine with aura. Conclusion When patients with TIA or stroke, severe mood disorders, aura of migraine, dementia, MRI or CT showed subcortical white matter and basal ganglia widely abnormal changes, it is necessary to consider the CADASIL diagnosis.