CAJ | 학술논문

目的：观察恩度+化疗在非小细胞肝癌（NSCLC）病症治疗中的效果与心血管不良反应发生概率。方法随机将我院收治的68例NSCLC患者分成甲乙两组各34例，分别给予其单纯化疗与恩度+化疗处理，对两组治疗效果与心血管不良反应进行对比分析。结果经统计学分析发现，两组患者在治疗后，均获得了一定成效，其中，甲组治疗总有效率为67.65%，同乙组88.24%相比，差异显著（P<0.05）；但恩度联合化疗组未增加化疗药物骨髓抑制等毒性反应，两组在血小板与白细胞改变方面差异无统计学意义（P>0.05）；心血管反应发生方面，在窦性心动过速与血压波动方面比较，存在着差异，具有统计学意义（P<0.05)。结论给予临床NSCLC患者以恩度+化疗处理，明显提高其近期治疗效果，出现心血管不良反应在可控范围内，并不会诱发骨髓抑制出现，整体效果理想。
목적：관찰은도+화료재비소세포간암（NSCLC）병증치료중적효과여심혈관불량반응발생개솔。방법수궤장아원수치적68례NSCLC환자분성갑을량조각34례，분별급여기단순화료여은도+화료처리，대량조치료효과여심혈관불량반응진행대비분석。결과경통계학분석발현，량조환자재치료후，균획득료일정성효，기중，갑조치료총유효솔위67.65%，동을조88.24%상비，차이현저（P<0.05）；단은도연합화료조미증가화료약물골수억제등독성반응，량조재혈소판여백세포개변방면차이무통계학의의（P>0.05）；심혈관반응발생방면，재두성심동과속여혈압파동방면비교，존재착차이，구유통계학의의（P<0.05)。결론급여림상NSCLC환자이은도+화료처리，명현제고기근기치료효과，출현심혈관불량반응재가공범위내，병불회유발골수억제출현，정체효과이상。
ObjectiveTo observe degree + chemotherapy in non-small cell cancer (NSCLC) in the treatment of disease and cardiovascular adverse reaction probability.MethodRandomly to our hospital 68 cases of NSCLC patients into two groups of the 34 cases, party a and party b respectively given the simple chemotherapy and grace degrees plus chemotherapy treatment, the effect of two groups of treatment and cardiovascular adverse reactions were analyzed.ResultsThrough statistical analysis, two groups of patients after treatment, all obtained certain achievements, among them, the ifrst treatment the total effective rate was 67.65%, compared with group b 88.24%, signiifcant difference (P<0.05); But grace MDT group did not increase the chemotherapy drug toxicity reactions such as bone marrow suppression, two groups there was no statistically significant difference in platelet and leucocyte change (P>0.05); Cardiovascular reaction, on sinus tachycardia compared with blood pressure lfuctuate, there are differences, statistically signiifcant (P<0.05). ConclusionGives grace to the clinical NSCLC patients degree + chemotherapy treatment, improve its recent treatment effect, in cardiovascular adverse reaction under control, does not induce bone marrow suppression, the overall effect is ideal.