CAJ | 학술논문

黑素细胞移植是治疗稳定期白癜风的方法之一，主要包括培养的黑素细胞移植和表皮细胞悬液移植。近年来动物实验证实脂肪干细胞可代替角质形成细胞与黑素细胞共培养移植治疗白癜风。白癜风患者自体黑素细胞的移植效率可通过皮损周围皮肤归巢CD8＋T细胞活动性来进行预测，真皮间充质干细胞可作为黑素细胞移植治疗白癜风的辅助剂。本文综述黑素细胞移植治疗白癜风的国内外进展，旨在为临床提供参考。
흑소세포이식시치료은정기백전풍적방법지일，주요포괄배양적흑소세포이식화표피세포현액이식。근년래동물실험증실지방간세포가대체각질형성세포여흑소세포공배양이식치료백전풍。백전풍환자자체흑소세포적이식효솔가통과피손주위피부귀소CD8＋T세포활동성래진행예측，진피간충질간세포가작위흑소세포이식치료백전풍적보조제。본문종술흑소세포이식치료백전풍적국내외진전，지재위림상제공삼고。
Transplantion of melanocytes is one of the methods in the treatment of vitiligo at stable stage, including cultured melanocyte transplantation and epidermal cells suspension transplantation. Co-culturing of melanocytes with adipose-derived stem cells may be a potential substitute for co-culturing with keratino-cytes. The efficiency of autologous melanocytes transplantation in vitiligo patients may be predicted by perile-sional skin-homing CD8+T cell activities and the dermal mesenchymal stem cells might be used as auxiliary agent to improve the efficacy. The progress on transplantion of melanocytes in the treatment of vitiligo is re-viewed.