CAJ | 학술논문

乳腺梭形细胞癌是一种罕见的乳腺癌亚型,具有肿瘤偏大、分期晚、组织学分级高、激素受体阴性的临床病理特点,易出现局部复发,淋巴结转移少见,血行转移常见,预后差.由于该病临床发病率较低,我们对其了解有限,如何早期发现、诊断及提高疗效是目前临床需要解决的问题.本文就梭形细胞癌的临床病理特征、诊断、治疗及预后作简要综述.
유선사형세포암시일충한견적유선암아형,구유종류편대、분기만、조직학분급고、격소수체음성적림상병리특점,역출현국부복발,림파결전이소견,혈행전이상견,예후차.유우해병림상발병솔교저,아문대기료해유한,여하조기발현、진단급제고료효시목전림상수요해결적문제.본문취사형세포암적림상병리특정、진단、치료급예후작간요종술.
Spindle cell carcinoma of the breast (SpCC) is a very rare variant of breast cancer characterized as large tumor size,high histological grade and high negative expression of hormone receptors and HER2/neu protein.It has a high tendency for local recurrence and distant metastasis,while the axillary lymph node metastasis is less common occured,which leads to poor outcomes.Given the relatively low incidence,our knowledge about SpCC is limited.The main unsolved obstacles are the early dection and diagnosis,and the improvement in treatments.Herein,this article reviewed the clinicopathologic characteristic,diagnosis,treatment and prognosis of the spindle cell carcinoma of breast.