CAJ | 학술논문

目的探究结核性胸膜炎患者治疗前后血清糖类抗原125(CA125)水平的变化及其临床意义.方法选择2010年6月到2013年6月在佛山市第二人民医院进行诊治的62例结核性胸膜炎患者(观察组)及60名健康人(对照组)为研究对象,分别在抗结核治疗前、治疗1个月和3个月后对血清CA125水平进行对比.结果观察组治疗前血清CA125水平明显高于对照组;观察组患者在抗结核治疗1个月后血清CA125水平比治疗前有显著降低,治疗3个月后血清CA125水平低于治疗1个月后和治疗前水平(P值均＜0.01).结论 CA125水平检测可以作为结核性胸膜炎患者诊断和疗效观察的指标之一.
목적 탐구결핵성흉막염환자치료전후혈청당류항원125(CA125)수평적변화급기림상의의.방법 선택2010년6월도2013년6월재불산시제이인민의원진행진치적62례결핵성흉막염환자(관찰조)급60명건강인(대조조)위연구대상,분별재항결핵치료전、치료1개월화3개월후대혈청CA125수평진행대비.결과 관찰조치료전혈청CA125수평명현고우대조조;관찰조환자재항결핵치료1개월후혈청CA125수평비치료전유현저강저,치료3개월후혈청CA125수평저우치료1개월후화치료전수평(P치균＜0.01).결론 CA125수평검측가이작위결핵성흉막염환자진단화료효관찰적지표지일.
Objective To explore serum carbohydrate antigen 125 (CA125) level in patients with tuberculous pleurisy before and after treatment,and its clinical significance.Methods From June 2010 to June 2013,62 cases of tuberculous pleurisy (observation group) and 60 cases of healthy people (control group) were selected as the research objects.The serum CA125 level was detected before treatment and after treatment for one month and three months.Results Serum CA125 level in the patients with tuberculous pleurisy was significantly higher than that in the control group.Serum CA125 level after treatment for one month was significantly lower than that before treatment in the observation group.Serum CA125 level after treatment for three months was lower than that before treatment and after treatment for one month (all P ＜0.01).Conclusions Serum CA125 level can be used as one of the important indexes of diagnosis and treatment of tuberculous pleurisy.