实用疼痛学杂志
實用疼痛學雜誌
실용동통학잡지
PAIN CLINIC JOURNAL
2015年
2期
120-123
,共4页
环氧化酶2抑制剂%头皮%神经传导阻滞%镇痛%神经外科手术
環氧化酶2抑製劑%頭皮%神經傳導阻滯%鎮痛%神經外科手術
배양화매2억제제%두피%신경전도조체%진통%신경외과수술
Cyclooxygenase 2 inhibitors%Scalp%Nerve block%Analgesia%Neurosurgical procedures
目的 探讨帕瑞昔布钠静脉注射联合头皮神经阻滞用于开颅术后镇痛的持续时间和镇痛效果.方法 择期行开颅术患者58例,随机分为阻滞组(n=29)和联用组(n=29).前者术前行头皮神经阻滞术,后者麻醉前先静脉注射帕瑞昔布钠,后行头皮神经阻滞术.观察术后0、1、2、4、8、12、24 h各时点疼痛视觉模拟评分(VAS)与术后0、1、2、4、12、24 h收缩压(SBP)、心率(HR)、呼吸频率(RR)、恶心呕吐评分与镇静评分.结果 两种镇痛方法术后镇痛时间、镇静效果、生命体征等指标组间比较差异无统计学意义(P＞0.05);呼吸频率的组间差异有统计学意义(P＜0.05),但无临床意义.联用组患者术后首次使用镇痛药的时间比阻滞组显著延长(P＜0.05),且术后24 h内追加镇痛药物的例数较少(P＜0.05).结论 帕瑞昔布钠静脉注射联用头皮神经阻滞是一种有效的开颅手术后镇痛方法.
目的 探討帕瑞昔佈鈉靜脈註射聯閤頭皮神經阻滯用于開顱術後鎮痛的持續時間和鎮痛效果.方法 擇期行開顱術患者58例,隨機分為阻滯組(n=29)和聯用組(n=29).前者術前行頭皮神經阻滯術,後者痳醉前先靜脈註射帕瑞昔佈鈉,後行頭皮神經阻滯術.觀察術後0、1、2、4、8、12、24 h各時點疼痛視覺模擬評分(VAS)與術後0、1、2、4、12、24 h收縮壓(SBP)、心率(HR)、呼吸頻率(RR)、噁心嘔吐評分與鎮靜評分.結果 兩種鎮痛方法術後鎮痛時間、鎮靜效果、生命體徵等指標組間比較差異無統計學意義(P＞0.05);呼吸頻率的組間差異有統計學意義(P＜0.05),但無臨床意義.聯用組患者術後首次使用鎮痛藥的時間比阻滯組顯著延長(P＜0.05),且術後24 h內追加鎮痛藥物的例數較少(P＜0.05).結論 帕瑞昔佈鈉靜脈註射聯用頭皮神經阻滯是一種有效的開顱手術後鎮痛方法.
목적 탐토파서석포납정맥주사연합두피신경조체용우개로술후진통적지속시간화진통효과.방법 택기행개로술환자58례,수궤분위조체조(n=29)화련용조(n=29).전자술전행두피신경조체술,후자마취전선정맥주사파서석포납,후행두피신경조체술.관찰술후0、1、2、4、8、12、24 h각시점동통시각모의평분(VAS)여술후0、1、2、4、12、24 h수축압(SBP)、심솔(HR)、호흡빈솔(RR)、악심구토평분여진정평분.결과 량충진통방법술후진통시간、진정효과、생명체정등지표조간비교차이무통계학의의(P＞0.05);호흡빈솔적조간차이유통계학의의(P＜0.05),단무림상의의.련용조환자술후수차사용진통약적시간비조체조현저연장(P＜0.05),차술후24 h내추가진통약물적례수교소(P＜0.05).결론 파서석포납정맥주사련용두피신경조체시일충유효적개로수술후진통방법.
Objective To evaluate the analgesic effect of parecoxib sodium injection combined with scalp nerve block in patient after craniotomy.Methods Fifty-eight patients undergoing selective craniotomy were randomly divided into block group (n=29) and combined group (n=29).All patients were treated with scalp nerve block before the operation in the block group.Patients in combined group received parecoxib sodium intravenous injection additionally before scalp nerve block.VAS was recorded at 0,1,2,4,8,12,24 h after the operation.The SBP,HR,RR,nausea vomiting score,sedation score were assessed at 0,1,2,4,12,24 h after the operation.Results There were no significant differences in the duration of analgesia,sedation,vital signs and other indices between the two groups (P ＞ 0.05).There was statistically significant difference in respiratory rate between the two groups (P ＜ 0.05),but no clinical significance.The time of first needed analgesics after the operation in combined group was significantly longer than that in block group (P ＜ 0.05) and the patients needed additional analgesic drugs within 24 h after the operation were significantly lower in combined group than those in bock group (P =0.046).Conclusion Parecoxib sodium injection combined with scalp nerve block is an effective method for postoperative analgesia in patient after craniotomy.
