天津医药
天津醫藥
천진의약
TIANJIN MEDICAL JOURNAL
2015年
8期
950-953
,共4页
寡核苷酸序列分析%肾病综合征%综述%基因芯片
寡覈苷痠序列分析%腎病綜閤徵%綜述%基因芯片
과핵감산서렬분석%신병종합정%종술%기인심편
oligonucleotide array sequence analysis%nephrotic syndrome%review%gene chip
肾病综合征是儿童常见的肾脏疾病，目前其发病机制尚未完全阐明。近年来基因芯片技术日渐成熟，广泛应用于多个领域。应用基因芯片技术可以从基因水平分析肾病综合征的致病机制和药物治疗的作用靶点。本文重点介绍基因芯片技术在肾病综合征中的应用现状及前景。
腎病綜閤徵是兒童常見的腎髒疾病，目前其髮病機製尚未完全闡明。近年來基因芯片技術日漸成熟，廣汎應用于多箇領域。應用基因芯片技術可以從基因水平分析腎病綜閤徵的緻病機製和藥物治療的作用靶點。本文重點介紹基因芯片技術在腎病綜閤徵中的應用現狀及前景。
신병종합정시인동상견적신장질병，목전기발병궤제상미완전천명。근년래기인심편기술일점성숙，엄범응용우다개영역。응용기인심편기술가이종기인수평분석신병종합정적치병궤제화약물치료적작용파점。본문중점개소기인심편기술재신병종합정중적응용현상급전경。
Nephrotic syndrome is a common kidney disease in childhood. Its pathogenesis has not been fully elucidat?ed. In recent years, gene chip is maturing and widely used in many fields. Its application in nephrotic syndrome could pro?vide important information of its pathogenesis and treatment target at gene level. This article reveiwed the current application of the gene chip technology and its prospects in the nephrotic syndrome.
