中华口腔医学杂志
中華口腔醫學雜誌
중화구강의학잡지
Chinese Journal of Stomatology
2015年
8期
469-473
,共5页
吴峻岭%张强%朱婷%葛建华%周传健
吳峻嶺%張彊%硃婷%葛建華%週傳健
오준령%장강%주정%갈건화%주전건
复合树脂类%弹性模量%微胶囊%自修复
複閤樹脂類%彈性模量%微膠囊%自脩複
복합수지류%탄성모량%미효낭%자수복
Composite resins%Elastic modulus%Microcapsule%Self-healing
目的 合成含聚合单体微胶囊的牙科新型自修复抗菌复合树脂,并探讨相关性能,为其进一步临床应用提供参考.方法 制备含聚合单体三乙二醇二甲基丙烯酸酯的微胶囊,分别以0、2.5％、5.0％、7.5％及10.0％质量分数添加至含长链烷基季铵盐新型纳米二氧化硅抗菌填料的复合树脂中,生成含聚合单体微胶囊的牙科新型自修复抗菌复合树脂(新型树脂组),以纳米瓷化复合树脂(Tetric N-Ceram)为对照.三点弯曲实验检测各组树脂弯曲强度和弹性模量(每组样本量为6);单刃V形切口梁法测试各组树脂断裂韧性及自修复效率(每组样本量为6),同时进行扫描电镜观察.结果 引入7.5％聚合单体微胶囊时,新型树脂组弯曲强度和弹性模量分别为(96.4±14.3) MPa和(6.2±1.1) GPa,与对照组[分别为(99.1±1 1.9) MPa和(6.1±1.1)GPa]差异均无统计学意义(P＞0.05);当聚合单体微胶囊质量分数为7.5％和10.0％时,新型树脂的自修复效率分别为(66.8±7.0)％和(79.3±9.7)％;扫描电镜示愈合面有黑色不规则薄膜覆盖.结论 含聚合单体微胶囊的牙科新型自修复抗菌复合树脂具有较强的自修复功能,展示了良好的临床应用前景.
目的 閤成含聚閤單體微膠囊的牙科新型自脩複抗菌複閤樹脂,併探討相關性能,為其進一步臨床應用提供參攷.方法 製備含聚閤單體三乙二醇二甲基丙烯痠酯的微膠囊,分彆以0、2.5％、5.0％、7.5％及10.0％質量分數添加至含長鏈烷基季銨鹽新型納米二氧化硅抗菌填料的複閤樹脂中,生成含聚閤單體微膠囊的牙科新型自脩複抗菌複閤樹脂(新型樹脂組),以納米瓷化複閤樹脂(Tetric N-Ceram)為對照.三點彎麯實驗檢測各組樹脂彎麯彊度和彈性模量(每組樣本量為6);單刃V形切口樑法測試各組樹脂斷裂韌性及自脩複效率(每組樣本量為6),同時進行掃描電鏡觀察.結果 引入7.5％聚閤單體微膠囊時,新型樹脂組彎麯彊度和彈性模量分彆為(96.4±14.3) MPa和(6.2±1.1) GPa,與對照組[分彆為(99.1±1 1.9) MPa和(6.1±1.1)GPa]差異均無統計學意義(P＞0.05);噹聚閤單體微膠囊質量分數為7.5％和10.0％時,新型樹脂的自脩複效率分彆為(66.8±7.0)％和(79.3±9.7)％;掃描電鏡示愈閤麵有黑色不規則薄膜覆蓋.結論 含聚閤單體微膠囊的牙科新型自脩複抗菌複閤樹脂具有較彊的自脩複功能,展示瞭良好的臨床應用前景.
목적 합성함취합단체미효낭적아과신형자수복항균복합수지,병탐토상관성능,위기진일보림상응용제공삼고.방법 제비함취합단체삼을이순이갑기병희산지적미효낭,분별이0、2.5％、5.0％、7.5％급10.0％질량분수첨가지함장련완기계안염신형납미이양화규항균전료적복합수지중,생성함취합단체미효낭적아과신형자수복항균복합수지(신형수지조),이납미자화복합수지(Tetric N-Ceram)위대조.삼점만곡실험검측각조수지만곡강도화탄성모량(매조양본량위6);단인V형절구량법측시각조수지단렬인성급자수복효솔(매조양본량위6),동시진행소묘전경관찰.결과 인입7.5％취합단체미효낭시,신형수지조만곡강도화탄성모량분별위(96.4±14.3) MPa화(6.2±1.1) GPa,여대조조[분별위(99.1±1 1.9) MPa화(6.1±1.1)GPa]차이균무통계학의의(P＞0.05);당취합단체미효낭질량분수위7.5％화10.0％시,신형수지적자수복효솔분별위(66.8±7.0)％화(79.3±9.7)％;소묘전경시유합면유흑색불규칙박막복개.결론 함취합단체미효낭적아과신형자수복항균복합수지구유교강적자수복공능,전시료량호적림상응용전경.
Objective To develop novel self-healing and antibacterial resin composite containing microcapsules filled with polymerizable healing monomer,and to measure its properties for further clinical application.Methods Microcapsules filled with healing monomer of triethylene glycol dimethacrylate were synthesized according to methods introduced in the previous research.Microcapsules were added into novel resin composite containing nano-antibacterial silica fillers grafted with long chain alkyl quaternary ammonium at mass fractions of 0,2.5％,5.0％,7.5％ or 10.0％.A commercial resin composite(Tetric N-Ceram) was used as control.Flexural test was used to measure resin composite flexural strength and elastic modulus.The single edge Ⅴ-notched beam method was used to measure fracture toughness and self-healing efficiency.Scanning electron microscope(SEM) was used to examine the fractured surface of selected specimen for investigation of fracture mechanisms.Results The flexural strength and elastic modulus of the resin composite were (96.4 ± 14.3) MPa and (6.2 ± 1.1) GPa respectively after incorporation of microcapsules up to 7.5％,and no significant difference was found between the experimental group and the control group[(99.1±1 1.9) MPa and (6.1±1.1) GPa] (P＞0.05).The self-healing efficiency of (66.8±7.0)％ and (79.3±9.7)％ were achieved for resin composite with microcapsule mass fractions at 7.5％ and 10.0％.SEM image showed that irregular films covered the fractured surface.Conclusions This novel self-healing and antibacterial resin composite containing microcapsules filled with polymerizable healing monomer exhibited a promising self-healing ability,which enabled itself well up for combating bulk fracture and secondary caries in clinical application.
