CAJ | 학술논문

目的：探讨糖尿病患者下肢胫神经形态学参数以及声像图特征与密歇根筛查量表（MNSI）评分之间的相关性，为糖尿病周围神经病变的早期诊断提供影像学信息。方法选取我院收治的95例2型糖尿病患者，以30例健康志愿者作为对照（A组）。根据MNSI评分结果，将糖尿病患者分为B组（32例，0~2.4分）、C组（31例，2.5~4.4分）及D组（32例，≥4.5分），高频超声检测4组对象胫神经的形态学参数以及声像图特征；分析MNSI评分与胫神经形态学参数的相关性。结果与A组相比，B组胫神经的横径无明显变化（P>0.05），C、D组胫神经的前后径、横径、截面积增大（均P<0.05）。C、D组胫神经声像图异常改变的发生率高于B组（P<0.05）。胫神经的前后径、横径、截面积与MNSI评分呈正相关（rs分别为0.656、0.657和0.681，均P<0.05）。结论 MNSI评分与胫神经超声形态学参数及声像图特征具有一定的相关性，且评分越高，胫神经超声表现异常的可能性越大。
목적：탐토당뇨병환자하지경신경형태학삼수이급성상도특정여밀헐근사사량표（MNSI）평분지간적상관성，위당뇨병주위신경병변적조기진단제공영상학신식。방법선취아원수치적95례2형당뇨병환자，이30례건강지원자작위대조（A조）。근거MNSI평분결과，장당뇨병환자분위B조（32례，0~2.4분）、C조（31례，2.5~4.4분）급D조（32례，≥4.5분），고빈초성검측4조대상경신경적형태학삼수이급성상도특정；분석MNSI평분여경신경형태학삼수적상관성。결과여A조상비，B조경신경적횡경무명현변화（P>0.05），C、D조경신경적전후경、횡경、절면적증대（균P<0.05）。C、D조경신경성상도이상개변적발생솔고우B조（P<0.05）。경신경적전후경、횡경、절면적여MNSI평분정정상관（rs분별위0.656、0.657화0.681，균P<0.05）。결론 MNSI평분여경신경초성형태학삼수급성상도특정구유일정적상관성，차평분월고，경신경초성표현이상적가능성월대。
Objective To examine the correlation between the ultrasonic feature of tibial nerve and the scores of Michi?gan neuropathy screening instrument(MNSI)in type 2 diabetic mellitus (T2DM) and to provide information for early diagno?sis of diabetic peripheral neuropathy(DPN). Methods Based on scores of MNSI, 95 cases of T2DM patients were divided into three different groups:group B(0-2.4 scores), C(2.5-4.4 scores)and D(≥4.5 scores). Ultrasound parameters of group A (n=30) were compared with group B (n=32), group C (n=31) and group D (n=32). These parameters includes nerves′s an?teroposterior dimension, transverse diameter, cross-sectional area and fasciculus echo, the"screen cloth"structure, epineuri?um and the demarcation with neighbourhood structures. Correlation of MNSI with ultrasound performance of tibia nerve was also tested. Results Compared with group A, transverse diameter in group B did not show a obvious change, but anteropos?teror dimension, transverse diameter, cross-sectional area in group C, group D all increase.(P < 0.05). Compared with group B,ultrasound alteration were more frequent in group C and group D(P<0.05), but there was no statistical difference on that between group C and group D(P>0.05). There was a positive correlation between the nerves′s anteroposterior di?mension, transverse diameter, cross-sectional area with MNSI, rs were 0.656、0.657 and 0.681 respectively (P<0.05 in all three cases). Conclusion Certain correlation was observed between MNSI and tibial never ultrasonic feature in T2DM pa?tients;the higher MNSI scores , the greater chance of presence of abnormal sonographic features of tibial nerve.