CAJ | 학술논문

目的：了解临床分离的肠球菌在医院感染中的分布及对抗菌药物的耐药性。为临床预防医院感染及抗感染治疗提供依据。方法回顾性分析2010年1月至2014年12月临床分离的331株肠球菌的分布及对抗菌药物的耐药性，并采用VITEK2 compact全自动细菌分析仪对331株肠球菌进行检测分析。结果2010年1月至2014年12月共分离出331株肠球菌，其中分离出粪肠球菌220株（66.7%），屎肠球菌99株（30%），鸟肠球菌12株（3.3%），以粪肠球菌为主。在各种临床标本分布中，以阴道分泌物为最高，其次为尿液。粪肠球菌对红霉素、青霉素、环丙沙星、四环素的耐药率较高，对氨苄西林、喹喏酮类、氨基糖苷类药物耐药率比屎肠球菌低，除红霉素和四环素外，屎肠球菌对其他抗菌药物的耐药率均高于粪肠球菌。均未发现耐万古霉素的菌株。结论肠球菌感染以粪肠球菌、屎肠球菌为主。临床治疗应根据微生物实验室提供的药敏试验结果，合理选用抗菌药物。并根据其分离株的耐药特点，选择相应的治疗方案，从而提高治疗效果。
목적：료해림상분리적장구균재의원감염중적분포급대항균약물적내약성。위림상예방의원감염급항감염치료제공의거。방법회고성분석2010년1월지2014년12월림상분리적331주장구균적분포급대항균약물적내약성，병채용VITEK2 compact전자동세균분석의대331주장구균진행검측분석。결과2010년1월지2014년12월공분리출331주장구균，기중분리출분장구균220주（66.7%），시장구균99주（30%），조장구균12주（3.3%），이분장구균위주。재각충림상표본분포중，이음도분비물위최고，기차위뇨액。분장구균대홍매소、청매소、배병사성、사배소적내약솔교고，대안변서림、규야동류、안기당감류약물내약솔비시장구균저，제홍매소화사배소외，시장구균대기타항균약물적내약솔균고우분장구균。균미발현내만고매소적균주。결론장구균감염이분장구균、시장구균위주。림상치료응근거미생물실험실제공적약민시험결과，합리선용항균약물。병근거기분리주적내약특점，선택상응적치료방안，종이제고치료효과。
Objective To understand clinical isolated enterococcus in distribution and the antimicrobial resistance of nosocomial infection. To provide basis for clinical prevention of hospital infection and anti-infection treatment. Methods A retrospective analysis from January 2010 to December 2014, 331 strains of clinical isolated enterococcus distribution and the antimicrobial resistance, and adopts VITEK2 compact automatic analyzer of 331 strains enterococcus bacteria detection analysis. Results From January 2010 to December 2014, a total of 331 strains isolated enterococcus, which isolated 220 strains (66.7%), in enterococcus excrement enterococcus strains (30%), 99 birds enterococcus strains (3.3%), 12 is given priority to with dung enterococcus. Among various kinds of distribution of clinical specimens, is the highest with vaginal discharge, followed by urine. Dung enterococcus to erythromycin, penicillin, and ciprolfoxacin, higher prevalence of tetracycline resistance, to ampicillin, quetiapine well ketone, aminoglycoside drug resistant rate is lower than excrement enterococcus, in addition to erythromycin and tetracycline, excrement enterococcus to other antimicrobial resistance were higher than dung enterococcus. Have found no vancomycin resistant strains. Conclusions Enterococcus infection is given priority to with dung enterococcus, excrement enterococcus. Clinical treatment should be according to the results of the microbiology laboratory provides the drug sensitive test of reasonable choice of antimicrobial agents. And according to the resistance characteristics of isolates, choose corresponding treatment, so as to improve treatment effect.