中华脑血管病杂志（电子版）
中華腦血管病雜誌（電子版）
중화뇌혈관병잡지（전자판）
CHINESE JOURNAL OF CEREBROVASCULAR DISEASES(ELECTRONIC VERSION)
2014年
2期
4-8
,共5页
脑出血%血肿周围组织%磁共振%灌注加权成像
腦齣血%血腫週圍組織%磁共振%灌註加權成像
뇌출혈%혈종주위조직%자공진%관주가권성상
Intracerebral hemorrhage%Perihematomal tissue%MRI%Perfusion weighted imaging
目的：应用磁共振灌注加权成像研究高血压脑出血急性期和亚急性期血肿周围组织脑血流量的改变。方法连续入组2011年10月至2013年9月期间在南通大学附属医院神经内科住院治疗的高血压脑出血（hypertensive intracerebral hemorrhage，HICH）患者24例。所有患者于发病第3天、14天进行MRI检查，应用灌注加权成像（perfusion weighted imaging，PWI）测定并计算血肿周围1 cm区域、血肿周围损伤区域和血肿远隔区域的相对脑血流量（relative cerebral blood flow，rCBF）。结果发病第3天、14天时，血肿周围1 cm区域、血肿周围损伤区域的rCBF均显著低于血肿远隔区域。与发病第3天相比，发病第14天时血肿周围1 cm区域、血肿周围损伤区域的rCBF均显著下降。结论高血压脑出血的急性期和亚急性期，血肿周围组织存在明显的低灌注，亚急性期比急性期更严重。磁共振灌注加权成像能清晰显示血肿周围组织的脑血流量改变，有一定的临床实用价值。
目的：應用磁共振灌註加權成像研究高血壓腦齣血急性期和亞急性期血腫週圍組織腦血流量的改變。方法連續入組2011年10月至2013年9月期間在南通大學附屬醫院神經內科住院治療的高血壓腦齣血（hypertensive intracerebral hemorrhage，HICH）患者24例。所有患者于髮病第3天、14天進行MRI檢查，應用灌註加權成像（perfusion weighted imaging，PWI）測定併計算血腫週圍1 cm區域、血腫週圍損傷區域和血腫遠隔區域的相對腦血流量（relative cerebral blood flow，rCBF）。結果髮病第3天、14天時，血腫週圍1 cm區域、血腫週圍損傷區域的rCBF均顯著低于血腫遠隔區域。與髮病第3天相比，髮病第14天時血腫週圍1 cm區域、血腫週圍損傷區域的rCBF均顯著下降。結論高血壓腦齣血的急性期和亞急性期，血腫週圍組織存在明顯的低灌註，亞急性期比急性期更嚴重。磁共振灌註加權成像能清晰顯示血腫週圍組織的腦血流量改變，有一定的臨床實用價值。
목적：응용자공진관주가권성상연구고혈압뇌출혈급성기화아급성기혈종주위조직뇌혈류량적개변。방법련속입조2011년10월지2013년9월기간재남통대학부속의원신경내과주원치료적고혈압뇌출혈（hypertensive intracerebral hemorrhage，HICH）환자24례。소유환자우발병제3천、14천진행MRI검사，응용관주가권성상（perfusion weighted imaging，PWI）측정병계산혈종주위1 cm구역、혈종주위손상구역화혈종원격구역적상대뇌혈류량（relative cerebral blood flow，rCBF）。결과발병제3천、14천시，혈종주위1 cm구역、혈종주위손상구역적rCBF균현저저우혈종원격구역。여발병제3천상비，발병제14천시혈종주위1 cm구역、혈종주위손상구역적rCBF균현저하강。결론고혈압뇌출혈적급성기화아급성기，혈종주위조직존재명현적저관주，아급성기비급성기경엄중。자공진관주가권성상능청석현시혈종주위조직적뇌혈류량개변，유일정적림상실용개치。
Objective To study alterations of cerebral blood flow in perihematomal tissue in acute and subacute hypertensive intracerebral hemorrhage with MRI perfusion weighted imaging.Methods 24 consecutive patients with hypertensive intracerebral hemorrhage (HICH) admitted to the department of neurology of the afifliated hospital of Nantong university from October 2011 to September 2013 were recruited in the study. All patients underwent magnetic resonance imaging at days 3 and 14 after symptom onset. The relative cerebral blood lfow (rCBF) was measured and calculated using perfusion weighted imaging (PWI) in the 1 cm-wide area around the hematoma, as well as in the damaged area around the hematoma and the ipsilateral remote area.Results The values of rCBF in the 1 cm-wide area around the hematoma and in the damaged area around the hematoma were signiifcantly lower than in the ipsilateral remote area at days 3 and 14 after symptom onset. Compared with day 3 after symptom onset, the values of rCBF in the 1 cm-wide area around the hematoma and in the damaged area around the hematoma were signiifcantly decreased at day 14 after symptom onset.Conclusions There exits pronounced hypoperfusion in the tissue around the hematoma during the phases of acute and subacute hypertensive intracerebral hemorrhage. MRI perfusion weighted imaging may contribute to display the alteration of cerebral blood lfow of perihematomal tissue, and be with certain clinical applicatin value.
