CAJ | 학술논문

目的：研究和探讨对重症监护病房呼吸机相关性肺炎患者采用抗生素降阶梯治疗的临床情况及效果。方法随机选择2012年6月-2014年6月以来，在该院重症监护病房进行治疗的呼吸机相关性肺炎患者88例。将他们根据抽签法划分成对照组和观察组(各有44例)，对照组实施常规治疗方法进行临床治疗，观察组使用抗生素降阶梯方法进行临床治疗，对两组患者的治疗效果进行分析、比较和统计。结果经过统计学分析显示，观察组患者在抗生素使用时间、机械通气时间、感染控制时间、住院时间以及临床总有效率(93.18%)方面均显著高于对照组的61.36%，组间对比的差异具有统计学意义(P<0.05)。结论使用抗生素降阶梯疗法对重症监护病房呼吸机相关性肺炎患者进行临床治疗的效果明显，治疗时间短。因此，它是一种科学、理想、有效的临床治疗方法。
목적：연구화탐토대중증감호병방호흡궤상관성폐염환자채용항생소강계제치료적림상정황급효과。방법수궤선택2012년6월-2014년6월이래，재해원중증감호병방진행치료적호흡궤상관성폐염환자88례。장타문근거추첨법화분성대조조화관찰조(각유44례)，대조조실시상규치료방법진행림상치료，관찰조사용항생소강계제방법진행림상치료，대량조환자적치료효과진행분석、비교화통계。결과경과통계학분석현시，관찰조환자재항생소사용시간、궤계통기시간、감염공제시간、주원시간이급림상총유효솔(93.18%)방면균현저고우대조조적61.36%，조간대비적차이구유통계학의의(P<0.05)。결론사용항생소강계제요법대중증감호병방호흡궤상관성폐염환자진행림상치료적효과명현，치료시간단。인차，타시일충과학、이상、유효적림상치료방법。
Objective To study and discuss the clinical situation and effect of de-escalation therapy for ventilator-associated pneu-monia in patients using antibiotics. Methods 88 cases treated with ventilator associated pneumonia patients in ICU were random selected in June 2012 to June 2014, They will be divided into two groups according to the draw method average (each group has 44 cases), the patients in the control group using conventional methods of clinical treatment, the observation group were treated with antibiotic escalation method in clinical treatment, and comparison, statistics and analysis of two groups of patients with clini-cal diagnosis and effect. Results The statistical comparison shows, patients in the observation group use time, mechanical ventila-tion time, infection control time, hospitalization time and the total clinical effective rate in antibiotics (93.18%) were significantly better than the control group (61.36%), differences between the groups were significant, with statistical significance (P<0.05). Conclusion The use of antibiotic de-escalation therapy for clinical treatment of ventilator-associated pneumonia in patients with obvious effect, short treatment time. Therefore, it is a kind of ideal, scientific, effective clinical treatment method.