中国医药导报
中國醫藥導報
중국의약도보
CHINA MEDICAL HERALD
2015年
22期
47-50
,共4页
李櫆%周中银%罗和生%刘玉兰
李櫆%週中銀%囉和生%劉玉蘭
리괴%주중은%라화생%류옥란
自身免疫性胰腺炎%临床表现%诊断%治疗
自身免疫性胰腺炎%臨床錶現%診斷%治療
자신면역성이선염%림상표현%진단%치료
Autoimmune pancreatitis%Clinical manifestation%Diagnosis%Therapy
自身免疫性胰腺炎(AIP)是一种罕见的,以无痛性梗阻性黄疸为主要临床表现,以淋巴浆细胞浸润、局限性胰头肿块或弥漫性胰腺肿胀为特征的慢性胰腺炎。该疾病被分为两个亚型,1型AIP称为淋巴浆细胞硬化性胰腺炎;2型AIP称为特发性导管中心性慢性胰腺炎。目前,人们对AIP知之甚少,且AIP在临床上与胰腺癌难以鉴别,极易漏诊及误诊。本文在广泛查阅国内外关于AIP的相关文献后,就其流行病学与发病机制、临床表现、组织学特征、血清学特征、影像学特征、诊断标准和治疗等进行综述,以加强对AIP的认识,减少对该疾病的误诊。
自身免疫性胰腺炎(AIP)是一種罕見的,以無痛性梗阻性黃疸為主要臨床錶現,以淋巴漿細胞浸潤、跼限性胰頭腫塊或瀰漫性胰腺腫脹為特徵的慢性胰腺炎。該疾病被分為兩箇亞型,1型AIP稱為淋巴漿細胞硬化性胰腺炎;2型AIP稱為特髮性導管中心性慢性胰腺炎。目前,人們對AIP知之甚少,且AIP在臨床上與胰腺癌難以鑒彆,極易漏診及誤診。本文在廣汎查閱國內外關于AIP的相關文獻後,就其流行病學與髮病機製、臨床錶現、組織學特徵、血清學特徵、影像學特徵、診斷標準和治療等進行綜述,以加彊對AIP的認識,減少對該疾病的誤診。
자신면역성이선염(AIP)시일충한견적,이무통성경조성황달위주요림상표현,이림파장세포침윤、국한성이두종괴혹미만성이선종창위특정적만성이선염。해질병피분위량개아형,1형AIP칭위림파장세포경화성이선염;2형AIP칭위특발성도관중심성만성이선염。목전,인문대AIP지지심소,차AIP재림상상여이선암난이감별,겁역루진급오진。본문재엄범사열국내외관우AIP적상관문헌후,취기류행병학여발병궤제、림상표현、조직학특정、혈청학특정、영상학특정、진단표준화치료등진행종술,이가강대AIP적인식,감소대해질병적오진。
Autoimmune pancreatitis (AIP) is a rare, chronic pancreatitis with a painless obstructive jaundice on mani-festation, lymphoplasmacytic infiltration and fibrosis on histology and limitations of the pancreatic head mass or diffuse swelling of the pancreas on imaging. The disease is divided into two subtypes, type 1 called lymphoplasmacytic scleros-ing pancreatitis which is took as a part of the systemic autoimmune disease, and type 2 called idiopathic duct-centric chronic pancreatitis. People understand poorly about the disease so far, and in clinic, it is always difficult to differenti-ate from pancreatic cancer, and easy to misdiagnose. In this paper, after extensive relevant literature about AIP con-sulted at home and abroad, the epidemiology, pathogenesis, clinical manifestations, histologic characteristics, serological characteristics, imaging features, diagnosis criteria and treatment were reviewed, in order to strengthen the understand-ing and reduce the misdiagnosis of AIP.