CAJ | 학술논문

目的：探讨颅脑损伤后合并高钠血症的临床治疗及高钠血症对预后的影响。方法回顾分析该院2007年1月-2014年12月间收治的重型颅脑损伤合并高钠血症63例患者临床资料，对比血钠高低对死亡率的影响，对比控制尿量组与非控制尿量组血钠恢复时间。结果轻度高钠组、中度高钠组、重度高钠组分别有17例、24例、22例，各组的死亡率分别为29.4%、45.8%、63.6%，轻度高钠组与重度高钠组间相比，差异有统计学意义(P<0.05)。控制尿量组28例，非控制尿量组18例，两组的血钠恢复正常所需的平均天数分别为(4.57±1.86)、(6.38±1.49)，两组相比差异有统计学意义(P<0.05)。结论颅脑损伤合并高钠血症血钠值越高，死亡率越高，除常规治疗外，控制尿量可明显缩短血钠恢复的时间。
목적：탐토로뇌손상후합병고납혈증적림상치료급고납혈증대예후적영향。방법회고분석해원2007년1월-2014년12월간수치적중형로뇌손상합병고납혈증63례환자림상자료，대비혈납고저대사망솔적영향，대비공제뇨량조여비공제뇨량조혈납회복시간。결과경도고납조、중도고납조、중도고납조분별유17례、24례、22례，각조적사망솔분별위29.4%、45.8%、63.6%，경도고납조여중도고납조간상비，차이유통계학의의(P<0.05)。공제뇨량조28례，비공제뇨량조18례，량조적혈납회복정상소수적평균천수분별위(4.57±1.86)、(6.38±1.49)，량조상비차이유통계학의의(P<0.05)。결론로뇌손상합병고납혈증혈납치월고，사망솔월고，제상규치료외，공제뇨량가명현축단혈납회복적시간。
Objective To discuss the clinical treatment of craniocerebral injury complicated with hypernatremia and the impact of Hypernatremia on its prognosis. Methods The clinical data of 63 patients with severe craniocerebral injury complicated with hy-pernatremia in the Department of Neurosurery of our hospital were retrospectively analyzed. The relationships between serum sodi-um level and the mortality were studied, and serum sodium recovery time was compared between the urine-output-control group and non-urine-output-control group. Results There were 17 cases, 24 cases, 22 cases in the mild, moderate and severe hyperna-tremia group with the mortality rate of 29.4%, 45.8%and 63.6%, respectively, and the difference between mild and severe hyper-natremia group was statistically significant, P<0.05. There were 28 cases and 18 cases in the urine-output-control group and non-urine-output-control group, respectively, with average serum sodium recovery time of 4.57±1.86、6.38±1.49, respectively, and the difference was statistically significant, P<0.05. Conclusion In patients with craniocerebral injury complicated with hypernatremia, high serum sodium level result indicates high mortality rate. In addition to routine therapy, the limitation of urine output can short-en the serum sodium recovery time.