CAJ | 학술논문

目的：使用体积描记法对婴幼儿急性下呼吸道感染（ ALRI）肺功能相关变化和预后进行评估，探讨体描应用于婴幼儿ALRI中的意义。方法选取2012年2月至2013年6月收治的ALRI患儿共计430例，根据患儿情况分成喘息组180例，非喘息组250例，并设置呼吸功能正常儿童共110例作为对照组，使用体描仪对FRC，Raw以及潮气呼吸参数进行测定，分析比较各组FRC、Raw等体描特征性项目和潮气呼吸项目之间的差异与相关性。结果喘息组TPTEF／TE、FRCp中位数、FRCp／kg、sReff、Reff及Reff／kg明显高于其他2组（ P ＜02．05）， VPTEF／VE低于其他2组（ P ＜0．05）。 FRCP、FRCP／kg、sReff、Reff及Reff／kg与TPTEF／TE，IVPTEF／VE呈负相关（ P ＜0．05）。同急性期相比，喘息组患儿恢复期的TPTEF／TE、VPTEF／VE无显著改善（ P ＞0．05），FRCP、FRCP／kg、sReff、Reff、Reff／kg等体描特有指标下降明显，差异均有统计学意义（ P ＜0．05）。结论体描在测定ALRI患儿肺功能方面可行性较强，能有效反应ALRI的呼吸功能变化，值得临床推广应用。
목적：사용체적묘기법대영유인급성하호흡도감염（ ALRI）폐공능상관변화화예후진행평고，탐토체묘응용우영유인ALRI중적의의。방법선취2012년2월지2013년6월수치적ALRI환인공계430례，근거환인정황분성천식조180례，비천식조250례，병설치호흡공능정상인동공110례작위대조조，사용체묘의대FRC，Raw이급조기호흡삼수진행측정，분석비교각조FRC、Raw등체묘특정성항목화조기호흡항목지간적차이여상관성。결과천식조TPTEF／TE、FRCp중위수、FRCp／kg、sReff、Reff급Reff／kg명현고우기타2조（ P ＜02．05）， VPTEF／VE저우기타2조（ P ＜0．05）。 FRCP、FRCP／kg、sReff、Reff급Reff／kg여TPTEF／TE，IVPTEF／VE정부상관（ P ＜0．05）。동급성기상비，천식조환인회복기적TPTEF／TE、VPTEF／VE무현저개선（ P ＞0．05），FRCP、FRCP／kg、sReff、Reff、Reff／kg등체묘특유지표하강명현，차이균유통계학의의（ P ＜0．05）。결론체묘재측정ALRI환인폐공능방면가행성교강，능유효반응ALRI적호흡공능변화，치득림상추엄응용。
Objective To evaluate the changes of lung function related to infantile acute lower respiratory infection (ALRI) and patient’s prognosis by means of plethysmography,and to explore the application value of plethysmography in infantile acute lower respiratory infection .Methods Four hundred and thirty infants with ALRI who were admitted into our hospital from February 2012 to June 2013 were enrolled in the study .The patients were divided into two groups:gasping group ( n =180) and non-gasping group ( n =250),besides,110 healthy infants were served as control group .The FRC,Raw and moisture respiratory parameters of all the subjects were detected by plethysmography , and the correlation between plethysmographic parameters including FRC ,Raw and moisture respiratory parameters was analyzed and compared .Results The TPTEF/TE,median FRCp, FRCp, FRCp/kg, sReff, Reff and Reff/kg in gasping group were significantly higher than those in the other two groups ( P <0.05),however, VPTEF/VE was significantly lower than that in the other two groups (P<0.05).The FRCP,FRCP/kg,sReff,Reff,Reff/kg were negatively correlated to TPTEF/TE and IVPTEF/VE.As compared with those in gasping group at acute period ,the TPTEF/TE and VPTEF/VE were not obviously improved in gasping group at recovery period ( P >0.05),but FRCP,FRCP/kg,sReff,Reff,Reff /kg were significantly decreased ( P <0.05). Conclus ion Plethysmography is greatly feasible in measuring lung function of infants with ALRI ,which can effectively reflect the changes of respiratory function of patients with ALRI ,therefore , it is worthy of clinical spreading application .