环球中医药
環毬中醫藥
배구중의약
GLOBAL TCM
2015年
8期
916-920
,共5页
心身疾病%证候%刚柔辨证%脑电地形图%δ波%θ波
心身疾病%證候%剛柔辨證%腦電地形圖%δ波%θ波
심신질병%증후%강유변증%뇌전지형도%δ파%θ파
Psychosomatic diseases%Syndrome%Rigid-gentle syndrome differentiation%Brain electrical activity mapping ( BEAM)%δ wave%θ Wave
目的：通过观察心身疾病患者脑电信号慢波δ和θ波的功率值改变,探究心身疾病“刚柔辨证”四种常见证候与脑电慢波改变的相关关系。方法“证病结合”“以方测证”为研究方法,采用脑电地形图为技术手段,把经显效方剂对应治疗2~8周后疗效为显效和临床痊愈的“刚柔辨证”主证为心肝火旺、心肝阴虚、肝郁气滞、肝郁脾虚证的患者治疗前脑电信号δ和θ波功率值与健康人对照组脑电信号δ和θ波功率值进行对照分析。其中心肝火旺证20例、心肝阴虚证32例、肝郁气滞证27例、肝郁脾虚证21例和健康人对照组23例。结果心肝阴虚证与正常人对照组比较,δ波在额区和额极区功率值增高(在FP1、F3、F4,P<0.005；在FP2,P<0.05),θ波在除了双颞区之外所有10个脑区功率值增高(P<0.005)。心肝火旺证、肝郁气滞证、肝郁脾虚证与正常人对照组比较,δ波和θ波功率值增高,以前头部为主,但此三组与对照组比较未见显著性差异。结论初步揭示“刚柔辨证”四种常见证候与脑电慢波改变的规律性及特异性表现,初步从脑电生理学角度揭示“刚柔辨证”理论的物质基础和证候实质。
目的：通過觀察心身疾病患者腦電信號慢波δ和θ波的功率值改變,探究心身疾病“剛柔辨證”四種常見證候與腦電慢波改變的相關關繫。方法“證病結閤”“以方測證”為研究方法,採用腦電地形圖為技術手段,把經顯效方劑對應治療2~8週後療效為顯效和臨床痊愈的“剛柔辨證”主證為心肝火旺、心肝陰虛、肝鬱氣滯、肝鬱脾虛證的患者治療前腦電信號δ和θ波功率值與健康人對照組腦電信號δ和θ波功率值進行對照分析。其中心肝火旺證20例、心肝陰虛證32例、肝鬱氣滯證27例、肝鬱脾虛證21例和健康人對照組23例。結果心肝陰虛證與正常人對照組比較,δ波在額區和額極區功率值增高(在FP1、F3、F4,P<0.005；在FP2,P<0.05),θ波在除瞭雙顳區之外所有10箇腦區功率值增高(P<0.005)。心肝火旺證、肝鬱氣滯證、肝鬱脾虛證與正常人對照組比較,δ波和θ波功率值增高,以前頭部為主,但此三組與對照組比較未見顯著性差異。結論初步揭示“剛柔辨證”四種常見證候與腦電慢波改變的規律性及特異性錶現,初步從腦電生理學角度揭示“剛柔辨證”理論的物質基礎和證候實質。
목적：통과관찰심신질병환자뇌전신호만파δ화θ파적공솔치개변,탐구심신질병“강유변증”사충상견증후여뇌전만파개변적상관관계。방법“증병결합”“이방측증”위연구방법,채용뇌전지형도위기술수단,파경현효방제대응치료2~8주후료효위현효화림상전유적“강유변증”주증위심간화왕、심간음허、간욱기체、간욱비허증적환자치료전뇌전신호δ화θ파공솔치여건강인대조조뇌전신호δ화θ파공솔치진행대조분석。기중심간화왕증20례、심간음허증32례、간욱기체증27례、간욱비허증21례화건강인대조조23례。결과심간음허증여정상인대조조비교,δ파재액구화액겁구공솔치증고(재FP1、F3、F4,P<0.005；재FP2,P<0.05),θ파재제료쌍섭구지외소유10개뇌구공솔치증고(P<0.005)。심간화왕증、간욱기체증、간욱비허증여정상인대조조비교,δ파화θ파공솔치증고,이전두부위주,단차삼조여대조조비교미견현저성차이。결론초보게시“강유변증”사충상견증후여뇌전만파개변적규률성급특이성표현,초보종뇌전생이학각도게시“강유변증”이론적물질기출화증후실질。
Objective To explore the relationship of four common syndromes of ‘Rigid-Gentle Syndrome Differentiation’ of psychosomatic diseases and δ and θ wave change in brain electrical activity mapping ( BEAM) . Methods Syndromes are the core while diseases are the complement. The accuracy of Syndrome Differentiation has been verifying by the curative effects of fixed traditional Chinese medicine ( TCM) prescription. Each case was summarized by curative effects according to efficacy standards of different diseases. BEAM was used as technical means. Each case has been measured by BEAM before treatment. 100 cases of the four syndromes of‘Hyperactivity of heart-fire and liver-fire’ ,‘Heart and liver yin deficiency ’ , ‘Stagnation of QI due to depression of the liver ’ and ‘Stagnation of liver-QI with deficiency of the spleen ’ which belong to the system of ‘Rigid-Gentle Syndrome Differentiation ’ were enrolled in this study, and in order the number of cases are 20, 32, 27 and 21. In addition, the control group is of 23 healthy volunteers. Results The syndrome of ‘Heart and liver yin deficiency’: the rising trend of δ wave power in frontal pole and frontal region (P<0. 005 in FP1, F3, F4 and P<0. 05 in FP2) and θ wave power in ten cortical areas except double temporal region(P<0. 005). The syndrome of ‘Hy-peractivity of heart-fire and liver-fire’ ,‘Stagnation of QI due to depression of the liver’ and‘Stagnation of liver-QI with deficiency of the spleen’:the rising trend of slow wave power includingδwave andθwave in forebrain, but no significant change compared with the control group. Conclusions This study has preliminarily demonstrated the regularities and specificities of slow wave change of four common syndromes of ‘Rigid-Gentle Syndrome Differentiation ’ compared with control group in BEAM. This study has preliminarily provided the evidences of the material bases and the nature of‘Rigid-Gentle Syndrome Differ-entiation’ of psychosomatic medicine from the aspects of BEAM.
