CAJ | 학술논문

目的：分析酒精性肝硬化患者应用复方甘草酸苷联合还原型谷胱甘肽治疗的临床疗效。方法选取于漯河市第六人民医院诊治的86例酒精性肝硬化患者作为观察对象，将其随机分为两组，其中观察组43例患者采用复方甘草酸苷联合还原型谷胱甘肽治疗，对照组43例患者则单用还原型谷胱甘肽治疗，对两组治疗情况进行观察，并对比两组治疗效果。结果经治疗两组均获得一定疗效，其中观察组总有效率（93.0%）高于对照组（65.1%），两组疗效比较差异有统计学意义（P<0.05）；且观察组患者临床症状改善及肝功能改善程度均明显优于对照组，组间比较差异有统计学意义（P<0.05）。结论复发甘草酸苷联合还原型谷胱甘肽治疗酒精性肝硬化，可有效消除患者临床症状，明显改善患者肝功能，其疗效显著，具有重要应用价值。
목적：분석주정성간경화환자응용복방감초산감연합환원형곡광감태치료적림상료효。방법선취우탑하시제륙인민의원진치적86례주정성간경화환자작위관찰대상，장기수궤분위량조，기중관찰조43례환자채용복방감초산감연합환원형곡광감태치료，대조조43례환자칙단용환원형곡광감태치료，대량조치료정황진행관찰，병대비량조치료효과。결과경치료량조균획득일정료효，기중관찰조총유효솔（93.0%）고우대조조（65.1%），량조료효비교차이유통계학의의（P<0.05）；차관찰조환자림상증상개선급간공능개선정도균명현우우대조조，조간비교차이유통계학의의（P<0.05）。결론복발감초산감연합환원형곡광감태치료주정성간경화，가유효소제환자림상증상，명현개선환자간공능，기료효현저，구유중요응용개치。
Objective To analyze the clinical effect of compound glycyrrhizin combined with re-duced glutathione on alcoholic liver cirrhosis patients. Methods Eighty-six patients with alcoholic liver cirrhosis in the sixth people’s hospital of Luohe were selected. They were divided into two groups ran-domly. The 43 cases in observation group were treated with compound glycyrrhizin combined with reduced glutathione. The 43 patients in control group were treated by reduced glutathione therapy. The effects of the two groups were compared. Results After treatment,the two groups all obtained certain effect. The total effective rate of observation group( 93%)was significantly higher than that of the control group (65. 1%),the difference was significant(P<0. 05). The improvement of clinical symptoms and liver function improvement were significantly better in the observation group than those in the control group, the difference was significant( P<0. 05 ). Conclusions The recurrence of glycyrrhizin combined with reduced glutathione on alcoholic cirrhosis can effectively eliminate the clinical symptoms,improve the pa-tients’liver function,the curative effect is remarkable,and has important application value.