中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2015年
15期
57-59
,共3页
胺碘酮%心力衰竭%快速型心率失常%临床效果
胺碘酮%心力衰竭%快速型心率失常%臨床效果
알전동%심력쇠갈%쾌속형심솔실상%림상효과
Amiodarone%Heart failure%Tacharrhythmia%Clinical effect
目的：探讨胺碘酮治疗心力衰竭合并快速型心律失常患者的临床效果。方法选取西山矿务局职工总医院2013年6月至2014年6月收治的68例心力衰竭合并快速型心律失常患者作为研究对象，按照随机分组法将其分为对照组和观察组，对照组给予抗心力衰竭和改善心律失常药物治疗，观察组在对照组基础上给予口服胺碘酮治疗，随访3个月后比较两组患者临床效果及不良反应的发生情况。结果观察组治疗后治疗总有效率为94.1%，对照组为76.5%，观察组明显高于对照组，差异有统计学意义（P <0.05）；两组治疗前左室射血分数（LVEF）比较差异未见统计学意义（P>0.05），治疗后两组患者LVEF均有改善，但观察组改善程度较对照组明显，差异有统计学意义（P<0.05）；观察组不良反应发生率为8.9%，对照组为14.7%，组间比较差异未见统计学意义（P>0.05）。结论胺碘酮在治疗心力衰竭合并快速型心律失常方面临床效果较佳，且安全有效，不良反应少，值得在临床推广应用。
目的：探討胺碘酮治療心力衰竭閤併快速型心律失常患者的臨床效果。方法選取西山礦務跼職工總醫院2013年6月至2014年6月收治的68例心力衰竭閤併快速型心律失常患者作為研究對象，按照隨機分組法將其分為對照組和觀察組，對照組給予抗心力衰竭和改善心律失常藥物治療，觀察組在對照組基礎上給予口服胺碘酮治療，隨訪3箇月後比較兩組患者臨床效果及不良反應的髮生情況。結果觀察組治療後治療總有效率為94.1%，對照組為76.5%，觀察組明顯高于對照組，差異有統計學意義（P <0.05）；兩組治療前左室射血分數（LVEF）比較差異未見統計學意義（P>0.05），治療後兩組患者LVEF均有改善，但觀察組改善程度較對照組明顯，差異有統計學意義（P<0.05）；觀察組不良反應髮生率為8.9%，對照組為14.7%，組間比較差異未見統計學意義（P>0.05）。結論胺碘酮在治療心力衰竭閤併快速型心律失常方麵臨床效果較佳，且安全有效，不良反應少，值得在臨床推廣應用。
목적：탐토알전동치료심력쇠갈합병쾌속형심률실상환자적림상효과。방법선취서산광무국직공총의원2013년6월지2014년6월수치적68례심력쇠갈합병쾌속형심률실상환자작위연구대상，안조수궤분조법장기분위대조조화관찰조，대조조급여항심력쇠갈화개선심률실상약물치료，관찰조재대조조기출상급여구복알전동치료，수방3개월후비교량조환자림상효과급불량반응적발생정황。결과관찰조치료후치료총유효솔위94.1%，대조조위76.5%，관찰조명현고우대조조，차이유통계학의의（P <0.05）；량조치료전좌실사혈분수（LVEF）비교차이미견통계학의의（P>0.05），치료후량조환자LVEF균유개선，단관찰조개선정도교대조조명현，차이유통계학의의（P<0.05）；관찰조불량반응발생솔위8.9%，대조조위14.7%，조간비교차이미견통계학의의（P>0.05）。결론알전동재치료심력쇠갈합병쾌속형심률실상방면림상효과교가，차안전유효，불량반응소，치득재림상추엄응용。
Objective To investigate the clinical effect of amiodarone on patients with tachyarrhythmia merger combined with heart failure. Methods Sixty-eight patients with arrhythmia and heart failure from June 2013 to June 2014 were selected as research subjects. They were divided into control group and observation group according to the randomization method. The control group was treated with anti-heart failure and improve cardiac disorders drug treatment,and the observation group was given oral amio-darone therapy. The clinical effects and adverse reactions occurrence were compared after 3 months follow-up. Results After effective treatment,the total effective rate of observation group was 94. 1%,and 76. 5% in the control group,the difference was significant(P<0. 05);The left ventricular ejection fraction(LVEF)of the two groups before treatment had no significant difference(P>0. 05);The improvement of LVEF after treatment in observation group was significantly higher than that in control group(P<0. 05);The rate of adverse reactions was 8. 9% in the observation group and 14. 7% in the control group,and the difference was not statistically significant(P>0. 05). Conclusions Amiodarone in the treatment of heart failure and tachyarrhythmia is safe and effective,and has better clinical results,so it is worthy of clinical application.
