CAJ | 학술논문

目的：比较介入治疗及甲氨蝶呤全身化疗对剖宫产术后瘢痕妊娠的治疗效果。方法将58例诊断为瘢痕妊娠的患者分为介入组和化疗组，栓塞组行双侧子宫动脉栓塞术+B超引导下清宫术。化疗组肌肉注射甲氨蝶呤注射液+B超引导下清宫术。观察2组患者术后血HCG恢复阴性时间、平均住院时间、术中出血量、病灶消失时间，月经恢复时间，治疗费用等，并进行比较。结果两组患者治疗后血HCG恢复阴性时间、平均住院时间、术中出血量、病灶消失时间及治疗费用的比较，差异均有统计学意义(P＜0.05)；两组患者治疗后月经恢复时间比较差异无统计学意义(P＞0.05)。结论介入治疗及甲氨蝶呤化疗对瘢痕妊娠的治疗均有效，但介入治疗比甲氨蝶呤全身化疗更安全，风险低，较彻底，但治疗费用昂贵。
목적：비교개입치료급갑안접령전신화료대부궁산술후반흔임신적치료효과。방법장58례진단위반흔임신적환자분위개입조화화료조，전새조행쌍측자궁동맥전새술+B초인도하청궁술。화료조기육주사갑안접령주사액+B초인도하청궁술。관찰2조환자술후혈HCG회복음성시간、평균주원시간、술중출혈량、병조소실시간，월경회복시간，치료비용등，병진행비교。결과량조환자치료후혈HCG회복음성시간、평균주원시간、술중출혈량、병조소실시간급치료비용적비교，차이균유통계학의의(P＜0.05)；량조환자치료후월경회복시간비교차이무통계학의의(P＞0.05)。결론개입치료급갑안접령화료대반흔임신적치료균유효，단개입치료비갑안접령전신화료경안전，풍험저，교철저，단치료비용앙귀。
Objective To compare the efficancy of uterine artery embolization and Methotrexate chemotherapy in treating of cesarean scar pregnancy. Methods 58 patients of uterine scar pregnancy after cesarean were divided into embolization group and methotrexate group. the patients in embolization group undergoing curettage under B-ultrasonic monitoring combined with uterine artery embolization. the patients in Chemotherapy group undergoing curettage under B-ultrasonic monitoring combined with methotrexate ( intramscular injection). The time of serum human chorionic gonadotroph (HCG) resolution, hospitalization time, the intraopertative blood loss, and the time of lesion disappearance, the recover time of menses were analyzed and compared between the two groups. Results There were statistic difference of the time of serum HCG resolution,hospitalization time,intraopertative blood loss,and the time of lesion disappearance between the two groups after treatment(P<0.05). There was no statistic difference of he recover time of menses between the two groups(P>0.05). Conclusion uterine artery embolization and methotrexate chemotherapy were effective in the treatment of scar pregnancy, but uterine artery embolization is more safe,low risky,more thoroughly than methotrexate chemotherapy,but treatment is expensive.