CAJ | 학술논문

采用 Goldeneye20A STR 试剂盒，对山西晋城汉族人群的遗传多态性进行调查，19个基因座等位基因频率分布均符合 Hardy-Weinberg 平衡（P ＞0.05），累积个人识别率和累积非父排除率分别为1?1.27×10-23和0.999999991。这19个 STR 基因座在晋城汉族人群中具有较高的个体识别能力和遗传多态性，对于法医学个体识别和亲子鉴定具有重要的应用价值。
채용 Goldeneye20A STR 시제합，대산서진성한족인군적유전다태성진행조사，19개기인좌등위기인빈솔분포균부합 Hardy-Weinberg 평형（P ＞0.05），루적개인식별솔화루적비부배제솔분별위1?1.27×10-23화0.999999991。저19개 STR 기인좌재진성한족인군중구유교고적개체식별능력화유전다태성，대우법의학개체식별화친자감정구유중요적응용개치。
The genetic polymorphism of 19 short tandem repeats (STR) loci in Han population in Jincheng Shanxi was studied using Goldeneye 20A STR Amplification Kit. 1233 unrelated individuals were investigated to obtain allele frequencies and forensic genetic data. No deviations of allelic frequency from Hardy-Weinberg equilibrium were observed (P>0.05). Heterozygosity (H) of 19 loci ranges from 0.639 to 0.919,matching probability (PM) 0.014 to 0.177; power of discrimination (DP) 0.806 to 0.987; polymorphism information content (PIC) 0.58~0.91; power exclusion (PE) 0.342~0.821.The cumulative discrimination power (CDP) and cumulative probability of exclusion (CPE) are 1?1.27×10-23 and 0.999999991, respectively. The result indicates that 19 STR loci are highly polymorphic and suitable for forensic personal identification and paternity testing in this area.