CAJ | 학술논문

目的：探讨肌钙蛋白I（cTnI）、肌红蛋白（MYO）和肌酸激酶同工酶（CK‐MB）在急性心肌梗死（AMI）中的早期诊断，比较它们在AMI诊断中的应用意义。方法采用化学发光法对126例AMI患者及82例非心肌梗死组进行cTnI、MYO和CK‐MB检测，对其结果进行比较分析。结果 cTnI、MYO、CK‐MB出现时间及达到峰值的时间都不同，AMI患者cTnI、MYO和CK‐MB联合检测的敏感度、特异度、阴性预测值、阳性预测值高于单项检测。结论 cTnI、MYO和CK‐MB的联合检测有助于早期确诊AMI。
목적：탐토기개단백I（cTnI）、기홍단백（MYO）화기산격매동공매（CK‐MB）재급성심기경사（AMI）중적조기진단，비교타문재AMI진단중적응용의의。방법채용화학발광법대126례AMI환자급82례비심기경사조진행cTnI、MYO화CK‐MB검측，대기결과진행비교분석。결과 cTnI、MYO、CK‐MB출현시간급체도봉치적시간도불동，AMI환자cTnI、MYO화CK‐MB연합검측적민감도、특이도、음성예측치、양성예측치고우단항검측。결론 cTnI、MYO화CK‐MB적연합검측유조우조기학진AMI。
Objective To explore the Troponin I(cTnI) ,myoglobin(MYO) and creatine kinase isoenzyme(CK‐MB) in early di‐agnosis of acute myocardial infarction(AMI) ,and compare their significance in the diagnosis of AMI .Methods used chemilumines‐cence method in 126 patients with AMI and 82 cases of myocardial infarction group to test cTnI ,MYO and CK‐MB ,the results were compared .Results The cTnI ,MYO ,CK‐MB quality appear time and peak time was different ,in patients with acute myocardial in‐farction(cTnI ,MYO and CK‐MB joint detection sensitivity ,specificity ,negative predictive value ,positive predictive value was higher than single test .Conclusion cTnI ,MYO and CK‐MB joint detection is helpful to early diagnosis of AMI .