CAJ | 학술논문

微粒的捕获与移动广泛应用在生物工程、医药、微装配、化学分析、材料性能评定等各个领域。基于微流体提出一种新型微粒捕获与移动方法：通过对向放置在微粒两端的微管，向微粒喷射流体，形成流场；利用流场在微粒表面形成的压力包容面来捕获﹑挟持微粒，实现微粒的捕获与移动。以微米级微粒为例，详细分析微粒捕获与移动原理，通过仿真讨论颗粒捕获和把持的流场条件，解析微流体捕获、移动颗粒的动态过程，并通过试验证明建立模型的正确性和提出方法的可行性。研究和试验结果表明，通过两支微管对向喷射流体可以捕获和移动微粒。根据微粒的大小，溶液的黏度等参数，合理匹配流场参数，提出的方法可以捕获和移动任意尺寸的微粒，并可以使其按照微管移动方向，控制微粒做定向、定量运动，实现无接触地微粒的位置控制。
미립적포획여이동엄범응용재생물공정、의약、미장배、화학분석、재료성능평정등각개영역。기우미류체제출일충신형미립포획여이동방법：통과대향방치재미립량단적미관，향미립분사류체，형성류장；이용류장재미립표면형성적압력포용면래포획﹑협지미립，실현미립적포획여이동。이미미급미립위례，상세분석미립포획여이동원리，통과방진토론과립포획화파지적류장조건，해석미류체포획、이동과립적동태과정，병통과시험증명건립모형적정학성화제출방법적가행성。연구화시험결과표명，통과량지미관대향분사류체가이포획화이동미립。근거미립적대소，용액적점도등삼수，합리필배류장삼수，제출적방법가이포획화이동임의척촌적미립，병가이사기안조미관이동방향，공제미립주정향、정량운동，실현무접촉지미립적위치공제。
Trapping and displacement of micro particles is extensively used in bioengineering, pharmaceuticals, micro-assembly, chemical analysis, and material performance evaluation. A microfluidic-based method for trapping and displacement of micro particles is presented. With this method, two identical microtubes are symmetrically aligned on both sides of a particle, which squirt inside fluid to produce a flow field. The particle is enveloped by a pressure surface which enables trapping and clamping the particle. This method is valid for micron-sized particles of arbitrary shapes and sizes. With micron-scale particles as examples, the mechanism of trapping and displacement is analyzed in detail, suitable fluid conditions of trapping and clamping particles are discussed through simulation, and dynamic process of trapping and displacement is analyzed. In addition, the feasibility of this method is verified by experiments. The results show that using a pair of aligned microtubes squirting fluid can trap and move micro particles. According to the particle size and fluid viscosity, micro particles of arbitrary sizes can be trapped and fixed with proper flow field parameters. This method is also capable of displacing the particle to some distance in a certain direction with the microtubes, thereby enabling noncontact position control of micro particles.