CAJ | 학술논문

目的：探讨 MR 扩散加权成像(DWI)在宫颈癌诊断中的价值。方法对100例经病理检查证实为宫颈癌的患者(其中,鳞癌64例、腺癌36例；高分化31例、中分化40例、低分化29例)及100例宫颈正常者行 DWI 检查,测量表观扩散系数(ADC)值。比较各组 ADC 值之间的差异。分析宫颈癌 ADC 值与病理级别的相关性。结果 DWI 图像上宫颈癌信号明显高于正常宫颈。宫颈癌与正常宫颈平均 ADC 值分别为(0.83±0.11)×10-3 mm2/s、(1.78±0.21)×10-3 mm2/s,差异有统计学意义(t =4.551,P <0.05)。宫颈鳞癌、腺癌平均 ADC 值分别为(0.82±0.12)×10-3 mm2/s、(0.98±0.13)×10-3 mm2/s,差异有统计学意义(t =1.341,P <0.05)。宫颈癌患者中高分化组、中分化组、低分化组 ADC 值差异均有统计学意义(P<0.05),宫颈癌患者 ADC 值与肿瘤病理级别呈负相关(r=-0.732, P <0.05)。结论 DWI 有助于鉴别宫颈癌与正常宫颈及评估宫颈癌的病理类型、分级。
목적：탐토 MR 확산가권성상(DWI)재궁경암진단중적개치。방법대100례경병리검사증실위궁경암적환자(기중,린암64례、선암36례；고분화31례、중분화40례、저분화29례)급100례궁경정상자행 DWI 검사,측량표관확산계수(ADC)치。비교각조 ADC 치지간적차이。분석궁경암 ADC 치여병리급별적상관성。결과 DWI 도상상궁경암신호명현고우정상궁경。궁경암여정상궁경평균 ADC 치분별위(0.83±0.11)×10-3 mm2/s、(1.78±0.21)×10-3 mm2/s,차이유통계학의의(t =4.551,P <0.05)。궁경린암、선암평균 ADC 치분별위(0.82±0.12)×10-3 mm2/s、(0.98±0.13)×10-3 mm2/s,차이유통계학의의(t =1.341,P <0.05)。궁경암환자중고분화조、중분화조、저분화조 ADC 치차이균유통계학의의(P<0.05),궁경암환자 ADC 치여종류병리급별정부상관(r=-0.732, P <0.05)。결론 DWI 유조우감별궁경암여정상궁경급평고궁경암적병리류형、분급。
Objective To explore the value of MR diffusion weighted imaging in the diagnosis of cervical cancer.Methods The ADC value of 100 cases (64 cases with squamous carcinoma,36 cases with adenocarcinoma,including 31 cases of highly differentia-ted group,40 cases of moderately differentiated group,29 cases of lowly differentiated group)with cervical cancer diagnosed by pathological examination and 100 cases with normal cervix were measured by diffusion weighted imaging (DWI).The ADC values of each group were compared,and correlation between the ADC values of cervical cancer and pathological level were analyzed.Results The signal of cervical cancer on DWI image was significantly higher than the normal cervix.The ADC values of cervical cancer and normal cervix was respectively (0.83±0.1 1)×10 -3 mm2/s,(1.78±0.21)×10 -3 mm2/s,these differences suggest a statistic mean-ing (t=4.55 1,P <0.05).There were significant difference between the mean ADC value of squamous carcinoma(0.82 ±0.12)× 10 -3 mm2/s and adenocarcinoma (0.98 ±0.13)× 10 -3 mm2/s(t = 1.341,P < 0.05 ).The differences of the ADC values between highly differentiated group,moderately differentiated group and lowly differentiated group of cervical cancer were statistically sig-nificant (P< 0.05).There is negative correlation between ADC value of cervical cancer and the grades of tumor (r=-0.732,P<0.05).Con-clusion DWI can help to differentiate cervical cancer from normal cervix,and to evaluate the pathological type and grade.