CAJ | 학술논문

目的：探讨鼻咽腺癌(NPAC)不同病理亚型的扩散规律及其预后因素。方法回顾性分析39例经病理确诊为 NPAC患者的临床及影像学资料。结果11例 CT/MRI 示颅神经受累,其中腺样囊性癌(ACC)7例,普通腺癌(CAC)和黏液表皮样癌(MEC)各2例(P <0.05)。CAC 淋巴结转移率为40%,ACC 为7.7%,MEC 为16.7%(P =0.035)。CT/MRI 颅神经受累与否5年总生存率(OS)及无病生存率(DFS)存在统计学差异(P <0.001；P =0.001)。对19例早期(Ⅰ~Ⅱ期)病例,手术治疗组与非手术治疗组5年 OS 存在显著统计学差异(P =0.038),DFS 无统计学差异(P =0.056)。结论 CT 及 MRI 在 NPAC 扩散规律的发现及预后随访中起着重要的作用。
목적：탐토비인선암(NPAC)불동병리아형적확산규률급기예후인소。방법회고성분석39례경병리학진위 NPAC환자적림상급영상학자료。결과11례 CT/MRI 시로신경수루,기중선양낭성암(ACC)7례,보통선암(CAC)화점액표피양암(MEC)각2례(P <0.05)。CAC 림파결전이솔위40%,ACC 위7.7%,MEC 위16.7%(P =0.035)。CT/MRI 로신경수루여부5년총생존솔(OS)급무병생존솔(DFS)존재통계학차이(P <0.001；P =0.001)。대19례조기(Ⅰ~Ⅱ기)병례,수술치료조여비수술치료조5년 OS 존재현저통계학차이(P =0.038),DFS 무통계학차이(P =0.056)。결론 CT 급 MRI 재 NPAC 확산규률적발현급예후수방중기착중요적작용。
Objective To analyze the different spreading patterns and the prognostic factors of nasopharyngeal adenocarcinoma (NPAC).Methods The clinical and radiological data of 39 pathologically confirmed consecutive cases of NPAC were retrospectively reviewed.Results In the 1 1 patients with CT/MRI-detected cranial nerve (CN)involvement,there were ACC (n=7),CAC (n=2)and MEC (n=2)(P <0.05).Lymph node metastasis occurred in 40% of CAC,7.7% of ACC and 1 6.7% of MEC (P =0.035). Significant differences were observed in 5 year OS and DFS rates between patients with and without CT/MRI-detected CN involve-ment (P <0.001;P =0.001).In 1 9 patients with early stage disease (stageⅠ-Ⅱ),significant difference was observed in 5 year OS rate between the surgical treatment group and non-surgical treatment group (P =0.038),and the difference was not significant in DFS (P =0.056).Conclusion CT and MRI are valuable tools not only for discovering the different spreading patterns of NPAC, but also for its prognosis.