CAJ | 학술논문

目的：探讨 MR 扩散张量成像(DTI)及扩散张量纤维束成像(DTT)在脊髓良性病变中的应用价值。方法采用1.5T MR 对30例脊髓良性病变患者及10例健康志愿者行常规 MR 及 DTI 序列扫描,并重组各组脊髓的白质纤维束。结果与正常对照组相比,髓外组-ⅠADC 值[(1.29±0.24)×10-3 mm2/s]轻度升高,FA 值(0.46±0.06)轻度降低(P <0.05),髓外组-ⅡADC 值[(2.03±0.19)×10-3 mm2/s]明显升高,FA 值(0.37±0.03)明显降低(P <0.05),髓内组 ADC 值[(1.71±0.24)×10-3 mm2/s]明显升高,FA 值(0.30±0.06)明显降低(P <0.05)。通过 DTT 技术主要显示出白质纤维束的受压、稀疏、减少、中断。结论 FA值、ADC 值的改变及 DTT 能定量评价脊髓受损的严重程度并立体显示纤维束受损情况。
목적：탐토 MR 확산장량성상(DTI)급확산장량섬유속성상(DTT)재척수량성병변중적응용개치。방법채용1.5T MR 대30례척수량성병변환자급10례건강지원자행상규 MR 급 DTI 서렬소묘,병중조각조척수적백질섬유속。결과여정상대조조상비,수외조-ⅠADC 치[(1.29±0.24)×10-3 mm2/s]경도승고,FA 치(0.46±0.06)경도강저(P <0.05),수외조-ⅡADC 치[(2.03±0.19)×10-3 mm2/s]명현승고,FA 치(0.37±0.03)명현강저(P <0.05),수내조 ADC 치[(1.71±0.24)×10-3 mm2/s]명현승고,FA 치(0.30±0.06)명현강저(P <0.05)。통과 DTT 기술주요현시출백질섬유속적수압、희소、감소、중단。결론 FA치、ADC 치적개변급 DTT 능정량평개척수수손적엄중정도병입체현시섬유속수손정황。
Objective To explore the application value of diffusion tensor imaging and diffusion tensor tractography in the benign lesion of spinal cord.Methods 30 cases with the benign lesions of spinal cord and 10 healthy volunteers underwent MRI and DTI scanning by 1.5T MR.Results Compared with normal control group,ADC values [(1.29±0.24)×10 -3 mm2/s]of extramedullary group-Ⅰwere increased slightly,and FA values (0.46±0.06)were decreased slightly(P <0.05).In extramedullary group-Ⅱ,ADC values [(2.03±0.19)×10-3 mm2/s]were significantly increased and FA values (0.37±0.03)decreased in the lesion level (P <0.05).The ADC values [(1.71±0.24)×10 -3 mm2/s]of intramedullary group was significantly elevated,and the FA values (0.30±0.06)was obviously reduced (P <0.05 ).The fiber tracts showed the abnormality of the white matter,including compression,sparseness, grow downwards,interruption and other changes.Conclusion The changes of the FA and ADC values,diffusion tensor imaging of the bundle can quantitatively evaluate the severity of spinal cord damage and stereo display fiber bundle damage.