医学信息
醫學信息
의학신식
MEDICAL INFORMATION
2015年
30期
51-51
,共1页
Eales病%视网膜静脉周围炎%内皮缩血管肽类%发病机制
Eales病%視網膜靜脈週圍炎%內皮縮血管肽類%髮病機製
Eales병%시망막정맥주위염%내피축혈관태류%발병궤제
Eales disease%Retinal periphlebitis%Endothelin-1%Etiopathogenesis
目的观察Eales病患者血浆内皮素-1(Endothelin-1,ET-1)水平，探讨其与Eales病的关系。方法①将所有受试对象(包括Eales病患者及正常对照组)进行常规的全身检查及眼科检查②荧光素眼底血管造影结果结合眼底检查确定Eales病的分期。③内皮素-1的测定采用放射免疫法。结果①患病组ET-1平均值高于正常对照组(<0.05)，差别有统计学意义。②患病组新生血管前期组和新生血管期组ET-1平均值比较>0.05，差别无统计学意义。③患病组中男性ET-1平均值比女性平均值含量高(<0.05)，差别有统计学意义。④患病组ET-1与年龄成正相关。结论 Eales病的发生可能与血浆内皮素的水平增高有关，具体机制有待进一步探讨。
目的觀察Eales病患者血漿內皮素-1(Endothelin-1,ET-1)水平，探討其與Eales病的關繫。方法①將所有受試對象(包括Eales病患者及正常對照組)進行常規的全身檢查及眼科檢查②熒光素眼底血管造影結果結閤眼底檢查確定Eales病的分期。③內皮素-1的測定採用放射免疫法。結果①患病組ET-1平均值高于正常對照組(<0.05)，差彆有統計學意義。②患病組新生血管前期組和新生血管期組ET-1平均值比較>0.05，差彆無統計學意義。③患病組中男性ET-1平均值比女性平均值含量高(<0.05)，差彆有統計學意義。④患病組ET-1與年齡成正相關。結論 Eales病的髮生可能與血漿內皮素的水平增高有關，具體機製有待進一步探討。
목적관찰Eales병환자혈장내피소-1(Endothelin-1,ET-1)수평，탐토기여Eales병적관계。방법①장소유수시대상(포괄Eales병환자급정상대조조)진행상규적전신검사급안과검사②형광소안저혈관조영결과결합안저검사학정Eales병적분기。③내피소-1적측정채용방사면역법。결과①환병조ET-1평균치고우정상대조조(<0.05)，차별유통계학의의。②환병조신생혈관전기조화신생혈관기조ET-1평균치비교>0.05，차별무통계학의의。③환병조중남성ET-1평균치비녀성평균치함량고(<0.05)，차별유통계학의의。④환병조ET-1여년령성정상관。결론 Eales병적발생가능여혈장내피소적수평증고유관，구체궤제유대진일보탐토。
Objective The study observes Eales patients plasma Endothelin-1 level and explores their relationship to Eales disease.Methods ①Have al subjects (including Eales patients and normal matched control group) accept the conventional body checks and ophthalmic examination. ②FFA and ophthalmic examination determine the stage of Eales disease. ③Endothelin-1 tests use radioimmunoassay. Results ①The average of the patient group's ET-1 is higher than the control group ( <0.05). The dif erence is significant in statistical significance.②The average of the patient group's ET-1 are compared between the proliferative stage's and the non-proliferative stage's. The result shows >0.05. The dif erence is insignificant in statistical significance. ③The average of the males' ET-1 in the patient group is higher than the females' ( <0.05).The dif erence is significant in statistical significance.4. ET-1 is positive correlation with age in the patient group. Conclusion The level of plasma ET-1 is associated with the Eales disease.
