齐齐哈尔医学院学报
齊齊哈爾醫學院學報
제제합이의학원학보
JOURNAL OF QIQIHAR MEDICAL COLLEGE
2015年
22期
3350-3351
,共2页
肺耐药蛋白%鼻咽癌%复发
肺耐藥蛋白%鼻嚥癌%複髮
폐내약단백%비인암%복발
LRP%Nasopharyngeal carcinoma%Recurrence
目的：了解肺耐药蛋白LRP（ lung resistance protein ，LRP）与鼻咽癌复发的关系。方法用免疫组化染色SP法对112例鼻咽癌的LRP进行检测。 LRP阳性的分为A组，LRP阴性的分为B组。放、化疗后随访，对比LRP阳性和阴性鼻咽癌患者的复发率。结果112例鼻咽癌患者中LRP的阳性表达率为48．21％。随访5年，29例复发，A组患者鼻咽癌复发率为42．59％，B组患者复发率为10．34％，两者差异有统计学意义（χ2＝15．155，P＜0．05）。结论 LRP阳性表达的鼻咽癌患者，复发率较高，预后不良。
目的：瞭解肺耐藥蛋白LRP（ lung resistance protein ，LRP）與鼻嚥癌複髮的關繫。方法用免疫組化染色SP法對112例鼻嚥癌的LRP進行檢測。 LRP暘性的分為A組，LRP陰性的分為B組。放、化療後隨訪，對比LRP暘性和陰性鼻嚥癌患者的複髮率。結果112例鼻嚥癌患者中LRP的暘性錶達率為48．21％。隨訪5年，29例複髮，A組患者鼻嚥癌複髮率為42．59％，B組患者複髮率為10．34％，兩者差異有統計學意義（χ2＝15．155，P＜0．05）。結論 LRP暘性錶達的鼻嚥癌患者，複髮率較高，預後不良。
목적：료해폐내약단백LRP（ lung resistance protein ，LRP）여비인암복발적관계。방법용면역조화염색SP법대112례비인암적LRP진행검측。 LRP양성적분위A조，LRP음성적분위B조。방、화료후수방，대비LRP양성화음성비인암환자적복발솔。결과112례비인암환자중LRP적양성표체솔위48．21％。수방5년，29례복발，A조환자비인암복발솔위42．59％，B조환자복발솔위10．34％，량자차이유통계학의의（χ2＝15．155，P＜0．05）。결론 LRP양성표체적비인암환자，복발솔교고，예후불량。
Objective To explore the relationship between LRP and nasopharyngeal carcinoma ( NPC ) recurrent.Methods Immunohistochemical methods were used to examine the expression of LRP in NPC .To follow up the patients after radiotherapy and chemotherapy .The patients of LRP positive were divided to group A , The patients of LRP negative were divided to group B , compared the recurrence rate of patients with NPC . Results The positive expression rate of LRP in 112 patients with NPC was 48.21%.There were 29 patients with recurrent.The recurrence rate is 42.59% in group A, The recurrence rate was 10.34% in group B.This difference shows statistical significance (χ2 =15.155,P<0.05).Conclusions The positive expression of LRP suggests that the recurrence rate is higher in NPC .
