CAJ | 학술논문

目的：探讨急性脑梗死患者血清C反应蛋白（CRP）水平的变化，及其对脑梗死病情判断的意义。方法检测2013年4月-2013年12月200例在该院就诊的急性脑梗死患者作为研究组，同期在该院体检的健康患者100例，作为对照组，对两组患者的血清CRP水平和急性脑梗死患者神经功能的缺损程度进行分析。结果研究组血清CRP平均含量明显高于对照组，差异具有统计学意义(P<0.05)；不同梗死面积患者的血清CRP及不同型的急性脑梗死患者的血清CRP对比分析，分别比较，差异具有统计学意义(P<0.05)；神经功能的缺损程度和血清CRP的水平呈正相关，差异有统计学意义(P<0.05)。结论血清CRP与急性脑梗死的发生有密切的关系，是一个独立的危险因素，随着病情的严重程度而增加，CRP水平在一定程度上能反映脑梗死的病变程度。
목적：탐토급성뇌경사환자혈청C반응단백（CRP）수평적변화，급기대뇌경사병정판단적의의。방법검측2013년4월-2013년12월200례재해원취진적급성뇌경사환자작위연구조，동기재해원체검적건강환자100례，작위대조조，대량조환자적혈청CRP수평화급성뇌경사환자신경공능적결손정도진행분석。결과연구조혈청CRP평균함량명현고우대조조，차이구유통계학의의(P<0.05)；불동경사면적환자적혈청CRP급불동형적급성뇌경사환자적혈청CRP대비분석，분별비교，차이구유통계학의의(P<0.05)；신경공능적결손정도화혈청CRP적수평정정상관，차이유통계학의의(P<0.05)。결론혈청CRP여급성뇌경사적발생유밀절적관계，시일개독립적위험인소，수착병정적엄중정도이증가，CRP수평재일정정도상능반영뇌경사적병변정도。
Objective To investigate the changes of serum C reactive protein (CRP) level in patients with acute cerebral infarction and the diagnosis value of cerebral infarction. Methods 200 cases were selected which patients with acute cerebral infarction as the study group in our hospital during April 2013 to December 2013, in the same period, 100 cases of patients with medical health were regarded as the control group. The two groups of patient's serum CRP level and the defection degree of nerve function in pa-tients with acute cerebral infarction were analyzed. Results The study group of average serum CRP levels was significantly higher than the control group, the difference was statistically significant (P< 0.05); the patient's serum CRP of different infarction area and different type of acute cerebral infarction were compared, the difference was statistically significant (P< 0.05); the defection degree of nerve function and serum CRP levels were positively correlated with statistical significance (P< 0.05). Conclusion The relationship between serum CRP and acute cerebral infarction is closely related, as an independent risk factor, it can be increased with the severity of the disease. CRP level can reflect the degree of cerebral infarction in a certain extent.